Contact us

Yadi Zhou

Project Scientist, PhD
Cleveland Clinic Genome Center, Cleveland Clinic Research

Jiansong Fang

Research Scholar, PhD
Cleveland Clinic Genome Center, Cleveland Clinic Research

Feixiong Cheng

Principal Investigator, PhD
Director, Cleveland Clinic Genome Center, Cleveland Clinic Research
[email protected]

>> Feixiong Cheng Laboratory
>> Genome Center

Citing AlzGPS

AlzGPS: a genome-wide positioning systems platform to catalyze multi-omics for Alzheimer's drug discovery Zhou Y, Fang J, Bekris L, Kim YH, Pieper AA, Leverenz J, Cummings J, Cheng F Alzheimers Res Ther. 2021;13(1):24. PubMed | PMC

References

Harnessing Endophenotypes and Using Network Medicine in Alzheimer's Drug Repurposing Fang J, Pieper AA, Bekris L, Lee G, Nussinov R, Leverenz J, Cummings J, Cheng F Medicinal Research Reviews. 2020;40(6):2386-2426. PubMed | PMC

Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease Fang J, Zhang P, Zhou Y, Chiang CW, Tan J, Hou Y, Stauffer S, Li L, Pieper AA, Cummings J, Cheng F Nat Aging. 2021;1:1175-1188. PubMed | PMC

Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer's disease Fang J, Zhang P, Wang Q, Chiang CW, Zhou Y, Hou Y, Xu J, Chen R, Zhang B, Lewis SJ, Leverenz, JB, Pieper AA, Li B, Li L, Cummings J, Cheng F Alzheimers Res Ther. 2022;14(1):7. PubMed | PMC

A genome-wide positioning systems network algorithm for in silico drug repurposing Cheng F, Lu W, Liu C, Fang J, Hou Y, Handy D, Wang R, Zhao Y, Yang Y, Huang J, Hill D, Vidal M, Eng C, Loscalzo J Nat Commun. 2019;10:3476. PubMed | PMC

Alzheimer's disease drug development pipeline: 2020 Cummings J, Lee G, Ritter A, Sabbagh M, Zhong K Alzheimers Dement (N Y). 2020;6:e12050. PubMed | PMC

Alzheimer's disease drug development pipeline: 2019 Cummings J, Lee G, Ritter A, Sabbagh M, Zhong K Alzheimers Dement (N Y). 2019;5:272-293. PubMed | PMC

Alzheimer's disease drug development pipeline: 2018 Cummings J, Lee G, Ritter A, Zhong K Alzheimers Dement (N Y). 2018;4:195-214. PubMed | PMC