| # |
ID |
Title |
Status |
Agent |
Date updated |
Details |
| 1 |
NCT01951118 |
Olfactory Deficits and Donepezil Treatment in Cognitively Impaired Elderly |
Completed |
Donepezil |
July 13, 2020 |
|
| 2 |
NCT03811847 |
A Pilot of Methylphenidate in Mild Cognitive Impairment and Dementia Participants. |
Recruiting |
Methylphenidate |
June 30, 2020 |
|
| 3 |
NCT02989402 |
A Phase IV Study to Evaluate Safety, Tolerability and Effectiveness of Rivastigmine Patch 15cm2 in Patients With Severe Dementia of the Alzheimer's Type. |
Recruiting |
Rivastigmine |
May 27, 2020 |
|
| 4 |
NCT02087865 |
Effects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's Disease |
Recruiting |
Donepezil |
April 7, 2020 |
|
| 5 |
NCT03703856 |
Biomarker Predictors of Memantine Sensitivity in Patients With Alzheimer's Disease |
Recruiting |
Memantine |
March 6, 2020 |
|
| 6 |
NCT03073876 |
Detecting an Early Response to Donepezil With Measures of Visual Attention |
Active, not recruiting |
Donepezil |
Feb. 26, 2020 |
|
| 7 |
NCT03185208 |
Lithium As a Treatment to Prevent Impairment of Cognition in Elders |
Recruiting |
Lithium cation |
Jan. 10, 2020 |
|
| 8 |
NCT01832350 |
Nuedexta in the Treatment of Pseudobulbar Affect in Patients With Alzheimer's Disease |
Terminated |
Dextromethorphan, Quinidine |
Oct. 29, 2019 |
|
| 9 |
NCT00626210 |
Modafinil Treatment for Sleep/Wake Disturbances in Older Adults |
Terminated |
Modafinil |
Oct. 28, 2019 |
|
| 10 |
NCT03082755 |
Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's Disease |
Recruiting |
Gabapentin enacarbil |
Oct. 25, 2019 |
|
| 11 |
NCT03441516 |
Effect of Choline Alphoscerate on Cognitive Function in Alzheimer's Dementia |
Active, not recruiting |
Choline alfoscerate, Aripezil |
Oct. 23, 2019 |
|
| 12 |
NCT02703636 |
NextStep:Study to Evaluate Safety,Efficacy & Tolerability of Rivastigmine Patch in Mild to Moderate Alzheimer's Patients. |
Completed |
Rivastigmine |
Sept. 12, 2019 |
|
| 13 |
NCT02931136 |
Early Diagnosis and Early Treatment of Alzheimer's Disease Based on Senile Plaque Imaging |
Not yet recruiting |
Huperzine A |
April 16, 2019 |
|
| 14 |
NCT02553928 |
Comparison of Once Daily and Twice Daily Dosing on Safety and Tolerability of Memantine in Patients With Alzheimer |
Completed |
Memantine |
March 14, 2019 |
|
| 15 |
NCT02787746 |
Safety and Efficacy of Donepezil in Mild to Moderate Alzheimer's Disease |
Completed |
Donepezil |
March 5, 2019 |
|
| 16 |
NCT00276510 |
A Study of EGb 761® (Tanakan®) in Dementia of Alzheimer Type Onset in Patients Suffering From Memory Complaints |
Completed |
Ginkgo biloba |
Jan. 15, 2019 |
|
| 17 |
NCT00245206 |
Side Effects of Newer Antipsychotics in Older Adults |
Completed |
Aripiprazole, Olanzapine, Risperidone |
Dec. 17, 2018 |
|
| 18 |
NCT00571064 |
The Effectiveness And Safety Of Donepezil Hydrochloride (E2020) In Subjects With Mild To Severe Alzheimer's Disease Residing In An Assisted Living Facility |
Completed |
Donepezil |
Sept. 27, 2018 |
|
| 19 |
NCT00009191 |
The Depression in Alzheimer's Disease Study (DIADS) |
Completed |
Sertraline |
Aug. 20, 2018 |
|
| 20 |
NCT01585272 |
Tolerability of Rivastigmine Before and After Switching From Oral Formulation to Transdermal Patch in Alzheimer's Dementia |
Completed |
Rivastigmine (ENA713) |
April 18, 2018 |
|
| 21 |
NCT00792662 |
Improving Function, Quality of Life, Glycemia in Diabetics With Dementia |
Withdrawn |
Methylphenidate |
March 29, 2018 |
|
| 22 |
NCT03454646 |
Comparison of Therapeutic Strategies With Cholinesterase Inhibitors (SOS TRIAL) |
Not yet recruiting |
Donepezil, Galantamine, Rivastigmine |
March 6, 2018 |
|
| 23 |
NCT01354444 |
Trial of Carvedilol in Alzheimer's Disease |
Completed |
Carvedilol |
Feb. 6, 2018 |
|
| 24 |
NCT01142336 |
Effects of Simvastatin on Biomarkers |
Completed |
Simvastatin |
July 28, 2017 |
|
| 25 |
NCT03168997 |
Memantine Treatment in Alzheimer's Disease Patients |
Unknown status |
Memantine |
May 30, 2017 |
|
| 26 |
NCT03151382 |
A Based on PEEG and PET Study of Anxiolytic Treatment to Improve Cognitive Function in Patients With Alzheimer Disease |
Unknown status |
Tandospirone, Donepezil |
May 12, 2017 |
|
| 27 |
NCT00254033 |
Apathy Associated With Alzheimer's Disease |
Completed |
Dexmethylphenidate, Methylphenidate |
April 28, 2017 |
|
| 28 |
NCT00980785 |
Studying the Effects of Antihypertensives on Individuals at Risk for Alzheimer's |
Completed |
Ramipril |
March 29, 2017 |
|
| 29 |
NCT00731224 |
Compliance and Tolerability of Rivastigmine Transdermal Patch 10 cm² in Patients With Probable Alzheimer's Disease. |
Completed |
Rivastigmine |
March 28, 2017 |
|
| 30 |
NCT01047579 |
A 12 Week, Multicenter, Open Label Evaluation of Caregiver Preference, Safety and Tolerability of Exelon® Patch (Rivastigmine Transdermal) in Patients With Alzheimer's Disease |
Completed |
Rivastigmine |
Feb. 24, 2017 |
|
| 31 |
NCT01948791 |
16w Interventional Study on Titration and Dose/Efficacy Assessment of Exelon in Chinese Alzheimer's Disease Patients |
Completed |
Rivastigmine (ENA713) |
Feb. 13, 2017 |
|
| 32 |
NCT01529619 |
Efficacy, Safety and Tolerability of Rivastigmine Patch in Patients With Mild to Moderate Alzheimer's Disease Switched From Cholinesterase Inhibitors |
Completed |
Rivastigmine |
Nov. 18, 2016 |
|
| 33 |
NCT02955706 |
Assessment the Efficacy of Acetyl-L-carnitine in Patient With Alzheimer's Disease |
Unknown status |
Acetylcarnitine |
Nov. 8, 2016 |
|
| 34 |
NCT02648906 |
A Clinical Trial for an Evaluation of Choline Alfoscerate and Donepezil for Cognitive Improvements of Patients With Cerebrovascular Injury in Alzheimer Patients |
Unknown status |
Choline alfoscerate |
Nov. 2, 2016 |
|
| 35 |
NCT02097056 |
Safety and Efficacy of Donepezil HCl 23 mg in Patients With Moderate to Severe Alzheimer's Disease |
Completed |
Donepezil |
June 27, 2016 |
|
| 36 |
NCT00009217 |
Treatment of Behavioral Symptoms in Alzheimer's Disease |
Completed |
Haloperidol |
May 24, 2016 |
|
| 37 |
NCT00385684 |
Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT) |
Completed |
Acetaminophen, Hydrocodone |
Nov. 20, 2015 |
|
| 38 |
NCT00495820 |
Methylphenidate for Apathy in Alzheimer's Dementia: A Controlled Study |
Completed |
Methylphenidate |
Nov. 20, 2015 |
|
| 39 |
NCT01822951 |
Cerebrolysin Compared to Donepezil in Patients With Mild to Moderate Dementia of Alzheimer's Type (DAT) |
Withdrawn |
Donepezil, Cerebrolysin |
Oct. 26, 2015 |
|
| 40 |
NCT01119638 |
Escitalopram Treatment for BPSD in Alzheimer's Disease in Comparison to Risperidone |
Completed |
Escitalopram, Risperidone |
June 24, 2015 |
|
| 41 |
NCT00375557 |
Safety and Efficacy of Divalproex and Quetiapine in Elderly Alzheimer's Dementia Patients |
Withdrawn |
Valproic Acid, Quetiapine |
May 27, 2015 |
|
| 42 |
NCT02444637 |
Open Label Trial of Rivastigmine Patch in Subjects With Mild to Moderate Stage AD Having Coexisting svCVD |
Unknown status |
Rivastigmine |
May 14, 2015 |
|
| 43 |
NCT01122329 |
A Positron Emission Tomography (PET) Study Evaluating Brain Metabolism of a Medical Food in Alzheimer's Disease |
Completed |
Caprylidene |
March 23, 2015 |
|
| 44 |
NCT00933608 |
Effects of Memantine on Magnetic Resonance (MR) Spectroscopy in Subjects at Risk for Alzheimer's Disease |
Completed |
Memantine |
Oct. 21, 2014 |
|
| 45 |
NCT01841125 |
Escitalopram for the Treatment of Depression in Alzheimer's Disease |
Completed |
Escitalopram |
Aug. 13, 2014 |
|
| 46 |
NCT01849042 |
Effect of Memantine Oral Pump on Language in Patients With Probable Alzheimer's Disease |
Unknown status |
Donepezil, Memantine |
Aug. 13, 2014 |
|
| 47 |
NCT00476008 |
Delaying the Progression of Driving Impairment in Individuals With Mild Alzheimer's Disease |
Completed |
Memantine |
Aug. 11, 2014 |
|
| 48 |
NCT00403520 |
Hippocampus Study: Comparative Effect of Donepezil 10mg/d and Placebo on Clinical and Radiological Markers |
Completed |
Donepezil |
July 14, 2014 |
|
| 49 |
NCT01409564 |
Cilostazol Augmentation Study in Dementia |
Completed |
Cilostazol |
May 13, 2014 |
|
| 50 |
NCT01181921 |
The CIRCADIAN Study: Evaluation of Modulating Effect of Galantamine on Circadian Rhythm in Patients With Mild to Moderate Alzheimer's Disease |
Terminated |
Galantamine |
May 1, 2014 |
|
| 51 |
NCT01478633 |
Evaluation of Efficacy and Safety of Galantamine in Patients With Dementia of Alzheimer's Type Who Failed to Benefit From Donepezil |
Completed |
Galantamine |
March 26, 2014 |
|
| 52 |
NCT00042172 |
Treatment for Early Memory Loss |
Completed |
Donepezil, Ginkgo biloba |
March 3, 2014 |
|
| 53 |
NCT00551161 |
Magnetic Resonance Spectroscopy Study of Memantine in Alzheimer's Disease |
Completed |
Memantine |
Jan. 28, 2014 |
|
| 54 |
NCT00165750 |
Correlation Between Regional Brain Volume and Response to Donepezil Treatment in AD Patients |
Terminated |
Donepezil |
Nov. 20, 2013 |
|
| 55 |
NCT00208819 |
A Comparison of Two Standard Therapies in the Management of Dementia With Agitation |
Completed |
Risperidone, Quetiapine, Olanzapine, Valproic Acid |
Nov. 13, 2013 |
|
| 56 |
NCT00948766 |
Effects of Rivastigmine Patch on Activities of Daily Living and Cognition in Patients With Severe Dementia of the Alzheimer's Type (ACTION) (Study Protocol CENA713DUS44, NCT00948766) and a 24 Week Open-label Extension to Study CENA713DUS44 |
Completed |
Rivastigmine |
Aug. 28, 2013 |
|
| 57 |
NCT01921972 |
The Efficacy of a Combination Regimen in Patients With Mild to Moderate Probable Alzheimer's Disease |
Completed |
Galantamine, Memantine |
Aug. 14, 2013 |
|
| 58 |
NCT00417482 |
Antipsychotic Discontinuation in Alzheimer's Disease |
Completed |
Risperidone |
April 24, 2013 |
|
| 59 |
NCT00369603 |
Functional Brain Imaging of Medication Treatment Response in Mild Alzheimer's Disease Patients |
Terminated |
Galantamine, Donepezil |
April 11, 2013 |
|
| 60 |
NCT00177671 |
Antidepressant Medication Plus Donepezil for Treating Late-life Depression |
Completed |
Escitalopram, Venlafaxine, Duloxetine, Donepezil |
Feb. 6, 2013 |
|
| 61 |
NCT01054976 |
The Efficacy of Galantamine Treatment on Attention in Patients With Alzheimer's Disease |
Completed |
Galantamine |
Dec. 24, 2012 |
|
| 62 |
NCT00711204 |
Evaluating The Impact Of Donepezil Hydrochloride (Aricept) On Behavioral And Psychological Symptoms In Patients With Severe Alzheimer's Disease |
Withdrawn |
Donepezil |
Dec. 10, 2012 |
|
| 63 |
NCT00862940 |
A Clinical Study Evaluating the Effects of Memantine on Brain Atrophy in Patients With Alzheimer's Disease |
Completed |
Memantine |
Sept. 3, 2012 |
|
| 64 |
NCT00381381 |
The Clinical Response of Choline Acetyltransferase and Apolipoprotein Epsilon Gene Polymorphisms to Donepezil in Alzheimer's Disease |
Completed |
Donepezil |
Aug. 31, 2012 |
|
| 65 |
NCT00401167 |
Memantine for Agitation and Aggression in Severe Alzheimer's Disease |
Completed |
Memantine |
May 25, 2012 |
|
| 66 |
NCT00165724 |
Alzheimer's Disease Long-term Follow-up Study (ALF Study) |
Completed |
Donepezil |
May 4, 2012 |
|
| 67 |
NCT00561392 |
Clinical Effectiveness of 10 cm^2 Rivastigmine Patch in Patients With Alzheimer's Disease |
Completed |
Rivastigmine |
April 16, 2012 |
|
| 68 |
NCT00260624 |
Escitalopram Treatment of Patients With Agitated Dementia |
Completed |
Escitalopram |
Feb. 24, 2012 |
|
| 69 |
NCT00234637 |
Rivastigmine Monotherapy and Combination Therapy With Memantine in Patients With Moderately Severe Alzheimer's Disease Who Failed to Benefit From Previous Cholinesterase Inhibitor Treatment |
Completed |
Rivastigmine, Memantine |
Nov. 17, 2011 |
|
| 70 |
NCT00649220 |
Memantine and Antipsychotics Use |
Terminated |
Memantine |
Sept. 26, 2011 |
|
| 71 |
NCT00622713 |
A 24 Week, Multicenter, Open, Evaluation of the Clinical Effectiveness of the Once-daily 10 cm^2 Rivastigmine Patch Formulation in Patients With Probable Alzheimer's Disease (EXTRA) |
Completed |
Rivastigmine |
July 26, 2011 |
|
| 72 |
NCT00035204 |
A Study of the Effects on Sleep, Attention, and Gastrointestinal Tolerance of Galantamine and Donepezil in Patients With Alzheimer's Disease |
Completed |
Galantamine |
June 8, 2011 |
|
| 73 |
NCT00230568 |
EARTH 413: A Study of Aricept in Hispanic Patients With Mild to Moderate Alzheimer's Disease (AD) |
Completed |
Donepezil |
April 1, 2011 |
|
| 74 |
NCT00549601 |
Convenience, Tolerability, and Safety of Change in the Administration of Rivastigmine From Capsules to a Transdermal Patch in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
Rivastigmine |
March 24, 2011 |
|
| 75 |
NCT00216515 |
The Efficacy of Galantamine on the Attention and the Frontal Function of the Patients With Dementia of Alzheimer Type |
Completed |
Galantamine |
Jan. 24, 2011 |
|
| 76 |
NCT00800709 |
Memantine and Changes of Biological Markers and Brain PET Imaging in Alzheimer's Disease |
Completed |
Memantine |
Dec. 3, 2010 |
|
| 77 |
NCT00706186 |
Safety and Feasibility of Sodium Oxybate in Mild Alzheimer's Disease Patients |
Terminated |
Sodium oxybate |
July 7, 2010 |
|
| 78 |
NCT01025466 |
Exelon Patch and Combination With Memantine Comparative Trial |
Completed |
Rivastigmine, Memantine |
May 19, 2010 |
|
| 79 |
NCT00303277 |
Do HMG CoA Reductase Inhibitors Affect Abeta Levels? |
Completed |
Simvastatin, Pravastatin |
April 13, 2010 |
|
| 80 |
NCT00469456 |
Effect of Memantine on Functional Communication in Patients With Alzheimer's Disease |
Completed |
Memantine |
Dec. 24, 2009 |
|
| 81 |
NCT00477659 |
Neural Correlates In Mild Alzheimer's Disease |
Completed |
Donepezil |
May 7, 2009 |
|
| 82 |
NCT00866060 |
Donepezil and Memantine in Moderate to Severe Alzheimer's Disease |
Unknown status |
Donepezil, Memantine |
March 20, 2009 |
|
| 83 |
NCT00505167 |
Memantine Versus Donepezil in Early Stages of Alzheimer's Disease |
Completed |
Memantine, Donepezil |
Dec. 29, 2008 |
|
| 84 |
NCT00267163 |
Brain Imaging and Mental Disorders of Aging Intervention |
Completed |
Donepezil |
Aug. 29, 2008 |
|
| 85 |
NCT00626613 |
The Relationship Between Risperdal Treatment and Quality of Life in Patients With Alzheimer's Disease and Behavioural and Psychological Symptoms of Dementia (BPSD) |
Unknown status |
Risperidone |
March 5, 2008 |
|
| 86 |
NCT00046358 |
The Effect of Short-Term Statins and NSAIDs on Levels of Beta-Amyloid, a Protein Associated With Alzheimer's Disease |
Completed |
Lovastatin, Ibuprofen |
March 4, 2008 |
|
| 87 |
NCT00334906 |
Study of Memantine in Assessment of Selected Measures of Volumetric Magnetic Resonance Imaging (MRI) and Cognition in Moderate AD (Alzheimer's Disease) |
Completed |
Memantine |
Jan. 7, 2008 |
|
| 88 |
NCT00104442 |
Study of the Effects of Current Drug Treatments on Levels of Certain Brain Chemicals in Alzheimer's Disease |
Completed |
Rivastigmine |
Dec. 21, 2007 |
|
| 89 |
NCT00305903 |
Safety and Tolerability of Rivastigmine With Add-on Memantine in Patients With Probable Alzheimer's Disease |
Completed |
Rivastigmine, Memantine |
Dec. 21, 2007 |
|
| 90 |
NCT00480870 |
The Effect of Anticholinesterase Drugs on Sleep in Alzheimer's Disease Patients |
Completed |
Donepezil |
Dec. 4, 2007 |
|
| 91 |
NCT00306124 |
Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dementia/Mild Cognitive Impairment |
Unknown status |
Levodopa |
Oct. 25, 2007 |
|
| 92 |
NCT00523666 |
Diffusion Tensor Weighted MRI in Alzheimer's Disease Modifying Treatment Effects of Galantamine (Reminyl®) |
Unknown status |
Galantamine |
Aug. 31, 2007 |
|
| 93 |
NCT00229333 |
Study of Escitalopram Versus Placebo in the Treatment of Depressive Syndrome in Alzheimer's Disease, Vascular Dementia, and Mixed Vascular and Alzheimer's Dementia |
Unknown status |
Escitalopram |
Aug. 29, 2006 |
|
| 94 |
NCT00142324 |
CALM-AD |
Unknown status |
Donepezil |
Dec. 14, 2005 |
|
| # |
ID |
Title |
Status |
Agent |
Date updated |
Details |
| 1 |
NCT02670083 |
A Study Evaluating the Efficacy and Safety of Crenezumab Versus Placebo in Participants With Prodromal to Mild Alzheimer's Disease (AD). |
Terminated |
Crenezumab |
July 16, 2020 |
|
| 2 |
NCT03114657 |
A Study of Crenezumab Versus Placebo to Evaluate the Efficacy and Safety in Participants With Prodromal to Mild Alzheimer's Disease (AD) |
Terminated |
Crenezumab |
July 16, 2020 |
|
| 3 |
NCT03446001 |
Safety and Efficacy of TRx0237 in Subjects With Alzheimer's Disease Followed by Open-Label Treatment |
Recruiting |
TRx0237 |
July 15, 2020 |
|
| 4 |
NCT02446132 |
Long Term, Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type |
Recruiting |
Dextromethorphan, Quinidine |
July 14, 2020 |
|
| 5 |
NCT03393520 |
Assessment of the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type |
Recruiting |
Dextromethorphan, Quinidine |
July 14, 2020 |
|
| 6 |
NCT03491150 |
An Open-Label Crenezumab Study in Participants With Alzheimer's Disease |
Terminated |
Crenezumab |
July 13, 2020 |
|
| 7 |
NCT01922258 |
Safety and Tolerability Study of Flexible Dosing of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type |
Completed |
Brexpiprazole |
July 7, 2020 |
|
| 8 |
NCT04339413 |
A Study to Evaluate the Safety and Tolerability of Long-term Administration of Gantenerumab in Participants With Alzheimer's Disease (AD) |
Recruiting |
Gantenerumab |
July 2, 2020 |
|
| 9 |
NCT04374253 |
A Study to Evaluate the Safety, Tolerability, and Efficacy of Long-term Gantenerumab Administration in Participants With Alzheimer's Disease (AD) |
Not yet recruiting |
Gantenerumab |
July 2, 2020 |
|
| 10 |
NCT04241068 |
A Study to Evaluate Safety and Tolerability of Aducanumab in Participants With Alzheimer's Disease Who Had Previously Participated in the Aducanumab Studies 221AD103, 221AD301, 221AD302 and 221AD205 |
Enrolling by invitation |
Aducanumab |
June 30, 2020 |
|
| 11 |
NCT03443973 |
Safety and Efficacy Study of Gantenerumab in Participants With Early Alzheimer's Disease (AD) |
Recruiting |
Gantenerumab |
June 17, 2020 |
|
| 12 |
NCT03444870 |
Efficacy and Safety Study of Gantenerumab in Participants With Early Alzheimer's Disease (AD) |
Recruiting |
Gantenerumab |
June 17, 2020 |
|
| 13 |
NCT01862640 |
A Phase 3, 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of 2 Fixed Doses of Brexpiprazole in the Treatment of Alzheimer's Agitation |
Completed |
Brexpiprazole |
June 16, 2020 |
|
| 14 |
NCT04408755 |
Assessment of the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type |
Not yet recruiting |
Dextromethorphan, Quinidine |
June 9, 2020 |
|
| 15 |
NCT02245568 |
Open-Label Study of Leuco-methylthioninium Bis(Hydromethanesulfonate) (LMTM) in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD) |
Terminated |
LMTM |
June 2, 2020 |
|
| 16 |
NCT03548584 |
A Trial to Evaluate the Safety, Efficacy, and Tolerability of Brexpiprazole in Treating Agitation Associated With Dementia of the Alzheimer's Type |
Recruiting |
Brexpiprazole |
May 11, 2020 |
|
| 17 |
NCT03594123 |
A 12-week Extension Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type |
Recruiting |
Brexpiprazole |
May 11, 2020 |
|
| 18 |
NCT01224106 |
A Study of Gantenerumab in Participants With Prodromal Alzheimer's Disease |
Active, not recruiting |
Gantenerumab |
May 5, 2020 |
|
| 19 |
NCT04187547 |
A Phase III Multi Regional Clinical Trial (MRCT) of Tricaprilin in Mild to Moderately Severe Probable Alzheimer's Disease With Optional Open Label Extension |
Not yet recruiting |
Tricaprylin |
May 5, 2020 |
|
| 20 |
NCT02051608 |
A Study of Gantenerumab in Participants With Mild Alzheimer Disease |
Active, not recruiting |
Gantenerumab |
May 1, 2020 |
|
| 21 |
NCT02547818 |
Safety and Efficacy Study of ALZT-OP1 in Subjects With Evidence of Early Alzheimer's Disease |
Active, not recruiting |
Cromoglicic acid, Ibuprofen |
May 1, 2020 |
|
| 22 |
NCT04229927 |
BPDO-1603 Intervention Trial in Patients With Moderate-to-severe Alzheimer's Disease |
Recruiting |
BPDO-1603 |
April 22, 2020 |
|
| 23 |
NCT02586909 |
12-Month Open-Label Extension Study of Intepirdine (RVT-101) in Subjects With Alzheimer's Disease: MINDSET Extension |
Terminated |
Intepirdine (RVT-101) |
April 17, 2020 |
|
| 24 |
NCT01872598 |
Masitinib in Patients With Mild to Moderate Alzheimer's Disease |
Active, not recruiting |
Masitinib |
April 7, 2020 |
|
| 25 |
NCT03486938 |
Study of AGB101 in Mild Cognitive Impairment Due to Alzheimer's Disease |
Recruiting |
AGB101 |
April 3, 2020 |
|
| 26 |
NCT03887455 |
A Study to Confirm Safety and Efficacy of BAN2401 in Participants With Early Alzheimer's Disease |
Recruiting |
BAN-2401 |
March 16, 2020 |
|
| 27 |
NCT03031184 |
Study of Mirtazapine for Agitation in Dementia |
Active, not recruiting |
Mirtazapine |
March 10, 2020 |
|
| 28 |
NCT02956486 |
A 24-Month Study to Evaluate the Efficacy and Safety of Elenbecestat (E2609) in Subjects With Early Alzheimer's Disease |
Active, not recruiting |
Elenbecestat |
Feb. 28, 2020 |
|
| 29 |
NCT03036280 |
A 24-Month Study to Evaluate the Efficacy and Safety of Elenbecestat (E2609) in Subjects With Early Alzheimer's Disease_ |
Active, not recruiting |
Elenbecestat |
Feb. 28, 2020 |
|
| 30 |
NCT02442765 |
Efficacy, Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type |
Completed |
Dextromethorphan, Quinidine |
Feb. 7, 2020 |
|
| 31 |
NCT03075241 |
Z-Drugs for Sleep Disorders in Alzheimer's Disease |
Recruiting |
Zolpidem |
Feb. 6, 2020 |
|
| 32 |
NCT02346201 |
Apathy in Dementia Methylphenidate Trial 2 |
Active, not recruiting |
Methylphenidate |
Jan. 21, 2020 |
|
| 33 |
NCT02008357 |
Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss |
Active, not recruiting |
Solanezumab |
Jan. 18, 2020 |
|
| 34 |
NCT03724942 |
Brexpiprazole for the Long-term Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's Type |
Recruiting |
Brexpiprazole |
Dec. 27, 2019 |
|
| 35 |
NCT02783573 |
A Study of Lanabecestat (LY3314814) in Participants With Mild Alzheimer's Disease Dementia |
Terminated |
Lanabecestat |
Dec. 3, 2019 |
|
| 36 |
NCT02972658 |
A Study of Lanabecestat (LY3314814) in Early Alzheimer's Disease Dementia |
Terminated |
Lanabecestat |
Dec. 3, 2019 |
|
| 37 |
NCT02477800 |
221AD301 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease |
Terminated |
Aducanumab |
Nov. 12, 2019 |
|
| 38 |
NCT02484547 |
221AD302 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease |
Terminated |
Aducanumab |
Nov. 12, 2019 |
|
| 39 |
NCT03283059 |
Octohydroaminoacridine Succinate Tablet for Mild-to-Moderate Alzheimer's Disease |
Recruiting |
Octohydroaminoacridine succinate, Donepezil |
Oct. 22, 2019 |
|
| 40 |
NCT02750306 |
Safety and Efficacy of Suvorexant (MK-4305) for the Treatment of Insomnia in Participants With Alzheimer's Disease (MK-4305-061) |
Completed |
Suvorexant |
Oct. 16, 2019 |
|
| 41 |
NCT02442778 |
Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type |
Completed |
Dextromethorphan, Quinidine |
Oct. 15, 2019 |
|
| 42 |
NCT02760602 |
A Study of Solanezumab (LY2062430) in Participants With Prodromal Alzheimer's Disease |
Terminated |
Solanezumab |
Oct. 10, 2019 |
|
| 43 |
NCT01900665 |
Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus Placebo |
Terminated |
Solanezumab |
Oct. 9, 2019 |
|
| 44 |
NCT01127633 |
Continued Safety Monitoring of Solanezumab (LY2062430) in Alzheimer's Disease |
Terminated |
Solanezumab |
Oct. 8, 2019 |
|
| 45 |
NCT01931566 |
Biomarker Qualification for Risk of Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease (AD) and Safety and Efficacy Evaluation of Pioglitazone in Delaying Its Onset |
Terminated |
Pioglitazone |
Sept. 16, 2019 |
|
| 46 |
NCT02284906 |
AD-4833/TOMM40_303 Extension Study of the Safety and Efficacy of Pioglitazone to Slow Cognitive Decline in Participants With Mild Cognitive Impairment Due to Alzheimer Disease |
Terminated |
Pioglitazone |
July 2, 2019 |
|
| 47 |
NCT03116126 |
Noradrenergic Add-on Therapy With Guanfacine |
Recruiting |
Guanfacine |
June 12, 2019 |
|
| 48 |
NCT01953601 |
Efficacy and Safety Trial of Verubecestat (MK-8931) in Participants With Prodromal Alzheimer's Disease (MK-8931-019) |
Terminated |
Verubecestat |
May 17, 2019 |
|
| 49 |
NCT02080364 |
Evaluation of the Efficacy and Safety of Azeliragon (TTP488) in Patients With Mild Alzheimer's Disease |
Terminated |
Azeliragon |
May 17, 2019 |
|
| 50 |
NCT02916056 |
2-Year Extension Study of Azeliragon in Subjects With Alzheimer's Disease (STEADFAST Extension) |
Terminated |
Azeliragon |
May 17, 2019 |
|
| 51 |
NCT03197740 |
A Multinational, Multi-center, Randomized, Double-blind, Active Comparator, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Donepezil Transdermal Patch in Patients With Alzheimer's Disease |
Recruiting |
Donepezil |
Feb. 20, 2019 |
|
| 52 |
NCT03108846 |
Escitalopram for Agitation in Alzheimer's Disease |
Recruiting |
Escitalopram |
Jan. 17, 2019 |
|
| 53 |
NCT02817906 |
ITI-007 for the Treatment of Agitation in Patients With Dementia, Including Alzheimer's Disease |
Terminated |
Lumateperone |
Dec. 20, 2018 |
|
| 54 |
NCT00838110 |
A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease |
Completed |
Latrepirdine |
Dec. 6, 2018 |
|
| 55 |
NCT02585934 |
Study Evaluating Intepirdine (RVT-101) in Subjects With Mild to Moderate Alzheimer's Disease on Donepezil: MINDSET Study |
Completed |
Intepirdine (RVT-101) |
Dec. 5, 2018 |
|
| 56 |
NCT02293915 |
An Efficacy and Safety Study of Sodium Oligo-mannurarate (GV-971) Capsule for the Treatment of Alzheimer's Disease |
Completed |
Sodium oligo-mannurarate |
Oct. 10, 2018 |
|
| 57 |
NCT03691519 |
Prevention of Cognitive Decline in Older Adults With Low Dha/Epa Index in Red Blood Cells |
Recruiting |
Omega-3 fatty acids |
Oct. 1, 2018 |
|
| 58 |
NCT02079246 |
Long-term Safety and Tolerability of Idalopirdine (Lu AE58054) as Adjunctive Treatment to Donepezil in Patients With Mild-moderate Alzheimer's Disease |
Completed |
Idalopirdine |
Aug. 10, 2018 |
|
| 59 |
NCT02550665 |
Optimal Dose Escalation Strategy to Successful Achievement of High Dose Donepezil 23mg |
Completed |
Donepezil |
Aug. 7, 2018 |
|
| 60 |
NCT00439166 |
Effects of Doxycycline and Rifampicin on Biomarkers of Alzheimer's Disease in the Cerebrospinal Fluid |
Completed |
Doxycycline, Rifampicin |
March 19, 2018 |
|
| 61 |
NCT01689233 |
Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild Alzheimer's Disease |
Completed |
TRx0237 |
March 14, 2018 |
|
| 62 |
NCT01689246 |
Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
TRx0237 |
March 14, 2018 |
|
| 63 |
NCT02006641 |
Idalopirdine in Patients With Mild-moderate Alzheimer's Disease Treated With Donepezil |
Completed |
Idalopirdine |
Feb. 20, 2018 |
|
| 64 |
NCT02006654 |
Study of Idalopirdine in Patients With Mild - Moderate Alzheimer's Disease Treated With an Acetylcholinesterase Inhibitor |
Completed |
Idalopirdine |
Feb. 7, 2018 |
|
| 65 |
NCT00818662 |
A Phase 3 Study Evaluating Safety and Effectiveness of Immune Globulin Intravenous (IGIV 10%) for the Treatment of Mild-to-Moderate Alzheimer's Disease |
Completed |
Human immunoglobulin G |
Nov. 24, 2017 |
|
| 66 |
NCT01524887 |
Phase 3 IGIV, 10% in Alzheimer's Disease |
Terminated |
Human immunoglobulin G |
Nov. 24, 2017 |
|
| 67 |
NCT00490568 |
Open-Label Extension Study Of Rosiglitazone XR As Adjunctive Therapy In Subjects With Mild-to-Moderate Alzheimers |
Terminated |
Rosiglitazone |
Nov. 13, 2017 |
|
| 68 |
NCT00550420 |
Study Of Rosiglitazone XR In Subjects With Mild-to-Moderate Alzheimers |
Terminated |
Rosiglitazone |
Nov. 8, 2017 |
|
| 69 |
NCT01736579 |
Long-Term Study of IGIV, 10% in Alzheimer's Disease |
Terminated |
Human immunoglobulin G |
Oct. 23, 2017 |
|
| 70 |
NCT02168920 |
Aripiprazole for the Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's Type |
Terminated |
Aripiprazole |
Oct. 16, 2017 |
|
| 71 |
NCT00099242 |
Efficacy and Safety of the Rivastigmine Transdermal Patch in Patients With Probable Alzheimer's Disease |
Completed |
Rivastigmine |
Oct. 13, 2017 |
|
| 72 |
NCT01955161 |
Study of Idalopirdine in Patients With Mild - Moderate Alzheimer's Disease Treated With Donepezil |
Completed |
Idalopirdine |
Sept. 19, 2017 |
|
| 73 |
NCT00348140 |
Rosiglitazone (Extended Release Tablets) As Adjunctive Therapy In Subjects With Mild To Moderate Alzheimer's Disease |
Completed |
Rosiglitazone |
Sept. 5, 2017 |
|
| 74 |
NCT00009204 |
Serotonergic Pharmacotherapy for Agitation of Dementia |
Completed |
Citalopram, Perphenazine |
June 16, 2017 |
|
| 75 |
NCT00428090 |
Rosiglitazone (Extended Release Tablets) As Monotherapy In Subjects With Mild To Moderate Alzheimer's Disease |
Completed |
Rosiglitazone |
May 19, 2017 |
|
| 76 |
NCT01047254 |
Bupropion for the Treatment of Apathy in Alzheimer's Dementia |
Completed |
Bupropion |
May 9, 2017 |
|
| 77 |
NCT00255086 |
The Effect of Memantine on Brain Structure and Chemistry in Alzheimer's Disease Patients |
Completed |
Memantine |
April 7, 2017 |
|
| 78 |
NCT01404169 |
A 24-weeks, Multi-center, Randomized, Double-blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Donepezil Hydrochloride in Chinese Subjects With Severe Alzheimer's Disease |
Completed |
Donepezil |
March 8, 2017 |
|
| 79 |
NCT02017340 |
A Phase III Trial of Nilvadipine to Treat Alzheimer's Disease |
Completed |
Nilvadipine |
March 6, 2017 |
|
| 80 |
NCT00219232 |
An Open-label Extension to Evaluate the Efficacy and Safety of the Rivastigmine Transdermal Patch in Patients With Probable Alzheimer's Disease |
Completed |
Rivastigmine |
Feb. 23, 2017 |
|
| 81 |
NCT00007189 |
Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT) |
Completed |
Naproxen, Celecoxib |
Oct. 19, 2016 |
|
| 82 |
NCT00675623 |
A Safety and Efficacy Study of Oral Dimebon in Patients With Mild-To-Moderate Alzheimer's Disease |
Completed |
Latrepirdine |
Sept. 27, 2016 |
|
| 83 |
NCT00829374 |
Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil |
Completed |
Latrepirdine |
Sept. 27, 2016 |
|
| 84 |
NCT00954590 |
A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease |
Terminated |
Latrepirdine |
Sept. 27, 2016 |
|
| 85 |
NCT01152216 |
An Extension of the CONCERT Protocol (DIM18) |
Terminated |
Latrepirdine |
Sept. 27, 2016 |
|
| 86 |
NCT01409694 |
Alzheimer's Disease - Input of Vitamin D With mEmantine Assay |
Completed |
Vitamin D, Memantine |
Sept. 22, 2016 |
|
| 87 |
NCT01614886 |
Randomized, Double-blind Study to Evaluate the Tolerability of 2 Different Titration Methods of Rivastigmine Patch in AD Patients (MMSE 10-20) |
Completed |
Rivastigmine (ENA713) |
Aug. 1, 2016 |
|
| 88 |
NCT00056524 |
Safety Study of AVP-923 in the Treatment of IEED (Involuntary Emotional Expression Disorder) Also Known as Pseudobulbar Affect (Episodes of Uncontrolled Crying and/or Laughter) |
Completed |
Dextromethorphan/Quinidine (AVP-923) |
July 14, 2016 |
|
| 89 |
NCT00676143 |
Study Evaluating the Safety and Efficacy of Bapineuzumab in Alzheimer Disease Patients |
Terminated |
Bapineuzumab |
June 10, 2016 |
|
| 90 |
NCT01969123 |
Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease |
Terminated |
Encenicline (EVP-6124) |
May 3, 2016 |
|
| 91 |
NCT01969136 |
Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease |
Terminated |
Encenicline (EVP-6124) |
May 3, 2016 |
|
| 92 |
NCT02004392 |
Study of the Safety and Clinical Effects of 2 Doses of EVP-6124 in Subjects With Alzheimer's Disease Who Complete Study EVP-6124-024 or EVP-6124-025 |
Terminated |
Encenicline (EVP-6124) |
May 3, 2016 |
|
| 93 |
NCT00667810 |
Study Evaluating The Efficacy And Safety Of Bapineuzumab In Alzheimer Disease Patients |
Terminated |
Bapineuzumab |
Jan. 8, 2016 |
|
| 94 |
NCT00998764 |
A Long-Term Safety And Tolerability Extension Study Of Bapineuzumab In Alzheimer Disease Patients |
Terminated |
Bapineuzumab |
Jan. 1, 2016 |
|
| 95 |
NCT02327182 |
Safety Study of MT-4666 in Subjects With Alzheimer's Disease |
Terminated |
Encenicline (MT-4666) |
Nov. 13, 2015 |
|
| 96 |
NCT01539031 |
Compare the Efficacy and Safety of Donepezil Hydrochloride 23 mg Treatment With Continuation of Donepezil Hydrochloride 10 mg Treatment in Japanese Subjects With Severe Alzheimer's Disease |
Completed |
Donepezil |
Sept. 17, 2015 |
|
| 97 |
NCT00743743 |
Pilot Study of the Effects of Resveratrol Supplement in Mild-to-moderate Alzheimer's Disease |
Withdrawn |
Resveratrol |
Aug. 24, 2015 |
|
| 98 |
NCT00174382 |
Vaspect Study - An Open-Label Trial Of Donepezil in Vascular and Mixed Dementia |
Terminated |
Donepezil |
March 24, 2015 |
|
| 99 |
NCT00594568 |
Effect of LY450139 on the Long Term Progression of Alzheimer's Disease |
Completed |
Semagacestat (LY450139) |
March 17, 2015 |
|
| 100 |
NCT00630851 |
A Study of the Efficacy and Safety of Aricept in Patients With Severe Alzheimer's Disease Who Are Living in Skilled Nursing Homes |
Completed |
Donepezil |
March 5, 2015 |
|
| 101 |
NCT00762411 |
Effects of LY450139, on the Progression of Alzheimer's Disease as Compared With Placebo |
Completed |
Semagacestat (LY450139) |
Feb. 16, 2015 |
|
| 102 |
NCT00160147 |
Treatment of Elderly Subjects With Psychosis and Behavioral Disturbances Associated With Dementia of the Alzheimer's Type |
Terminated |
Bifeprunox |
Feb. 9, 2015 |
|
| 103 |
NCT00071721 |
Valproate in Dementia (VALID) |
Completed |
Valproic Acid |
Sept. 25, 2014 |
|
| 104 |
NCT00440050 |
DHA (Docosahexaenoic Acid), an Omega 3 Fatty Acid, in Slowing the Progression of Alzheimer's Disease |
Completed |
Doconexent |
Sept. 25, 2014 |
|
| 105 |
NCT01035138 |
A Study of Semagacestat for Alzheimer's Patients |
Completed |
Semagacestat |
Sept. 25, 2014 |
|
| 106 |
NCT01399125 |
A 24-Week Efficacy, Safety and Tolerability of Rivastigmine Patch Study in Patients With Probable Alzheimer's Disease |
Completed |
Rivastigmine |
Aug. 4, 2014 |
|
| 107 |
NCT00235716 |
A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease |
Completed |
DL-alpha-Tocopherol, Memantine |
July 23, 2014 |
|
| 108 |
NCT00539305 |
Hormone and Information Processing Study |
Completed |
Testosterone |
July 14, 2014 |
|
| 109 |
NCT00478205 |
Comparison of 23 mg Donepezil Sustained Release (SR) to 10 mg Donepezil Immediate Release (IR) in Patients With Moderate to Severe Alzheimer's Disease |
Completed |
Donepezil |
July 11, 2014 |
|
| 110 |
NCT00566501 |
Open-Label Extension Study of 23 mg Donepezil SR in Patients With Moderate to Severe Alzheimer's Disease |
Completed |
Donepezil |
July 11, 2014 |
|
| 111 |
NCT00898807 |
Citalopram for Agitation in Alzheimer's Disease |
Completed |
Citalopram |
June 27, 2014 |
|
| 112 |
NCT00428389 |
Safety of Switching From Donepezil to Rivastigmine Patch in Patients With Probable Alzheimer's Disease |
Completed |
Rivastigmine |
June 11, 2014 |
|
| 113 |
NCT00814801 |
An Efficacy and Safety Study of Galantamine for the Treatment of Patients With Alzheimer's Disease |
Completed |
Galantamine |
April 17, 2014 |
|
| 114 |
NCT00423085 |
Efficacy and Safety of Rivastigmine Transdermal Patch in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
Rivastigmine |
Feb. 10, 2014 |
|
| 115 |
NCT00996918 |
A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients |
Terminated |
Bapineuzumab |
Jan. 1, 2014 |
|
| 116 |
NCT00937352 |
A Long-Term Safety and Tolerability Study in Subjects With Mild to Moderate Alzheimer's Disease |
Terminated |
Bapineuzumab |
Dec. 20, 2013 |
|
| 117 |
NCT00857649 |
Efficacy and Safety of Memantine in Moderate to Severe Alzheimer's Disease |
Terminated |
Memantine |
Dec. 5, 2013 |
|
| 118 |
NCT01438060 |
Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of Alzheimer's Type |
Completed |
Aripiprazole |
Dec. 2, 2013 |
|
| 119 |
NCT01249196 |
A Confirmatory Trial of SK-PC-B70M in Mild to Moderate Alzheimer's Disease |
Completed |
SK-PC-B70M |
Nov. 26, 2013 |
|
| 120 |
NCT00574132 |
Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Non-Carrier) |
Completed |
Bapineuzumab |
Nov. 25, 2013 |
|
| 121 |
NCT00575055 |
Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Carrier) |
Completed |
Bapineuzumab |
Nov. 25, 2013 |
|
| 122 |
NCT00036114 |
Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's Type |
Completed |
Aripiprazole |
Nov. 11, 2013 |
|
| 123 |
NCT00041678 |
Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's Type |
Completed |
Aripiprazole |
Nov. 11, 2013 |
|
| 124 |
NCT00095719 |
Intramuscular Aripiprazole in Acutely Agitated Patients Diagnosed With Dementia |
Completed |
Aripiprazole |
Nov. 11, 2013 |
|
| 125 |
NCT00679627 |
A Study of Galantamine Used to Treat Patients With Mild to Moderate Alzheimer's Disease |
Terminated |
Galantamine |
Sept. 19, 2013 |
|
| 126 |
NCT01940952 |
Zydena on Cognitive Function of Alzheimer's Disease Patients |
Unknown status |
Udenafil, Donepezil |
Sept. 12, 2013 |
|
| 127 |
NCT01867775 |
Mirtazapine for Sleep Disorders in Alzheimer's Disease |
Unknown status |
Mirtazapine |
June 4, 2013 |
|
| 128 |
NCT00010803 |
Ginkgo Biloba Prevention Trial in Older Individuals |
Completed |
Ginkgo biloba |
March 14, 2013 |
|
| 129 |
NCT00804271 |
Memantine and Validation of a New Alzheimer's Disease Scale |
Completed |
Memantine |
Feb. 22, 2013 |
|
| 130 |
NCT00904683 |
Effect of LY2062430 on the Progression of Alzheimer's Disease |
Completed |
Solanezumab (LY2062430) |
Dec. 13, 2012 |
|
| 131 |
NCT00678431 |
Randomized Trial of a Nutritional Supplement in Alzheimer's Disease |
Completed |
Resveratrol |
Nov. 15, 2012 |
|
| 132 |
NCT00939783 |
An Extension To The B1451027 Protocol To Evaluate The Long Term Safety And Tolerability Of Dimebon In Patients With Alzheimer's Disease |
Terminated |
Latrepirdine |
Nov. 14, 2012 |
|
| 133 |
NCT01142258 |
Trazodone for Sleep Disorders in Alzheimer's Disease |
Completed |
Trazodone |
Oct. 15, 2012 |
|
| 134 |
NCT00912288 |
A Phase 3 Efficacy Study Of Dimebon In Patients With Moderate To Severe Alzheimer's Disease |
Terminated |
Latrepirdine |
Oct. 2, 2012 |
|
| 135 |
NCT01066546 |
An Extension To The B1451006 Protocol To Evaluate The Safety and Efficacy of Dimebon In Subjects With Moderate-to-Severe Alzheimer's Disease |
Terminated |
Latrepirdine |
Oct. 2, 2012 |
|
| 136 |
NCT00905372 |
Effect of LY2062430 on the Progression of Alzheimer's Disease |
Completed |
Solanezumab (LY2062430) |
Sept. 25, 2012 |
|
| 137 |
NCT00506415 |
Comparative Efficacy, Safety, and Tolerability of Rivastigmine 10 and 15 cm^2 Patch in Patients With Alzheimer's Disease (AD) Showing Cognitive Decline |
Completed |
Rivastigmine |
Sept. 19, 2012 |
|
| 138 |
NCT00857233 |
Safety and Tolerability of Memantine in Moderate to Severe Alzheimer's Disease |
Terminated |
Memantine |
Aug. 29, 2012 |
|
| 139 |
NCT01594346 |
Multicenter Vitamin E Trial in Aging Persons With Down Syndrome |
Completed |
Vitamin E |
May 9, 2012 |
|
| 140 |
NCT01183806 |
Effects of Exercise and Rivastigmine on Quality of Life of Alzheimer's Disease Patients |
Completed |
Rivastigmine |
March 20, 2012 |
|
| 141 |
NCT00090116 |
The Safety and Efficacy of Neramexane in Patients With Moderate to Severe Alzheimer's Disease |
Completed |
Neramexane |
March 5, 2012 |
|
| 142 |
NCT00097916 |
An Evaluation of the Safety and Efficacy of Memantine in Agitated Patients With Moderate to Severe Alzheimer's Disease |
Completed |
Memantine |
March 5, 2012 |
|
| 143 |
NCT00624026 |
Memantine - Communication Study |
Completed |
Memantine |
Nov. 1, 2011 |
|
| 144 |
NCT00216593 |
Treatment of Severe Alzheimer's Disease: Evaluation of Efficacy and Safety of Galantamine Hydrobromide in a Controlled Study |
Completed |
Galantamine |
June 21, 2011 |
|
| 145 |
NCT01245530 |
An Efficacy and Safety Study of INM-176 for the Treatment of Patients With Alzheimer Type Dementia |
Completed |
Donepezil |
June 13, 2011 |
|
| 146 |
NCT00236431 |
A Study to Evaluate the Efficacy and Safety of Galantamine in Patients With Mild Cognitive Impairment |
Completed |
Galantamine |
June 8, 2011 |
|
| 147 |
NCT00236574 |
A Study to Evaluate the Efficacy and Safety of Galantamine in Patients With Mild Cognitive Impairment |
Completed |
Galantamine |
June 8, 2011 |
|
| 148 |
NCT00488670 |
Escitalopram and Depression in Elderly Alzheimer's Patients |
Terminated |
Escitalopram |
June 6, 2011 |
|
| 149 |
NCT00287742 |
A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Patients With Hallucinations and Delusions Associated With Alzheimer's Disease |
Terminated |
Risperidone |
May 24, 2011 |
|
| 150 |
NCT00253214 |
Placebo-Controlled Evaluation of Galantamine in the Treatment of Alzheimer's Disease: Safety and Efficacy of a Controlled-Release Formulation |
Completed |
Galantamine |
May 23, 2011 |
|
| 151 |
NCT00082602 |
Safety and Tolerability Study of Extended Release (ER) Galantamine in Alzheimer's Disease |
Completed |
Galantamine |
May 20, 2011 |
|
| 152 |
NCT00645190 |
A Randomized, Double-blind, Flexible Dose, Multicenter Study to Evaluate the Effectiveness and Safety of Galantamine IR in Mild to Moderate Alzheimer's Disease |
Completed |
Galantamine |
May 19, 2011 |
|
| 153 |
NCT00240695 |
A Follow-up Study to Assess Safety and Tolerability of Galantamine Treatment in Individuals With Mild Cognitive Impairment |
Completed |
Galantamine |
May 18, 2011 |
|
| 154 |
NCT00253188 |
A Study of the Safety and Effectiveness of Two Doses of Galantamine Versus Placebo in the Treatment of Patients With Alzheimer's Disease |
Completed |
Galantamine |
May 18, 2011 |
|
| 155 |
NCT00253201 |
A Study of the Safety and Effectiveness of Two Doses of Galantamine Versus Placebo in the Treatment of Patients With Alzheimer's Disease |
Completed |
Galantamine |
May 18, 2011 |
|
| 156 |
NCT00253227 |
A Study of the Safety and Effectiveness of a Flexible Dose of Galantamine Versus Placebo in the Treatment of Patients With Alzheimer's Disease |
Completed |
Galantamine |
May 18, 2011 |
|
| 157 |
NCT00261573 |
A Study of the Safety and Effectiveness of Galantamine Versus Placebo in the Treatment of Patients With Vascular Dementia or Mixed Dementia |
Completed |
Galantamine |
May 18, 2011 |
|
| 158 |
NCT00309725 |
A Cardiac Safety Study of Galantamine in the Treatment of Alzheimer's Disease. |
Completed |
Galantamine |
May 18, 2011 |
|
| 159 |
NCT00301574 |
An Efficacy and Safety Study of Galantamine for the Treatment of Patients With Alzheimer's Disease. |
Completed |
Galantamine |
May 17, 2011 |
|
| 160 |
NCT00096473 |
Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer's Disease |
Completed |
Donepezil |
April 1, 2011 |
|
| 161 |
NCT01172145 |
Treatment of Apathy in Alzheimer's Disease With Modafinil |
Completed |
Modafinil |
March 4, 2011 |
|
| 162 |
NCT00034762 |
Efficacy and Safety of Risperidone Compared With Placebo in the Treatment of Psychotic Symptoms in Patients With Alzheimer's Disease |
Completed |
Risperidone |
Feb. 1, 2011 |
|
| 163 |
NCT00304629 |
Long-term Safety and Efficacy of Galantamine in Alzheimer's Disease |
Completed |
Galantamine |
Feb. 1, 2011 |
|
| 164 |
NCT00216502 |
A Study of the Safety and Effectiveness of Galantamine in Patients With Alzheimer's Disease |
Completed |
Galantamine |
Jan. 24, 2011 |
|
| 165 |
NCT00249145 |
A Study of the Effectiveness and Safety of Risperidone in the Treatment of Behavioral Disturbances in Patients With Dementia |
Completed |
Risperidone |
Jan. 14, 2011 |
|
| 166 |
NCT00253123 |
A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Behavioral Disturbances in Patients With Dementia |
Completed |
Risperidone |
Dec. 3, 2010 |
|
| 167 |
NCT00249158 |
A Study of the Effectiveness and Safety of Risperidone in the Treatment of Behavioral Disturbances in Patients With Dementia |
Completed |
Risperidone |
Nov. 19, 2010 |
|
| 168 |
NCT00000176 |
Alzheimer's Disease Prevention Trial |
Completed |
Estradiol, Progesterone |
Nov. 5, 2010 |
|
| 169 |
NCT00322153 |
A Study of the Safety and Efficacy of Memantine in Moderate to Severe Alzheimer's Disease |
Completed |
Memantine |
Sept. 16, 2010 |
|
| 170 |
NCT00190021 |
Donepezil Treatment of Psychotic Symptoms in Dementia Patients |
Unknown status |
Donepezil |
Sept. 8, 2010 |
|
| 171 |
NCT00338117 |
Safety and Efficacy of High Dose, Rapid Titration Galantamine in Patients With Alzheimer's Disease |
Completed |
Galantamine |
April 28, 2010 |
|
| 172 |
NCT00000173 |
Memory Impairment Study (Mild Cognitive Impairment Study) |
Completed |
Vitamin E, Donepezil |
Dec. 11, 2009 |
|
| 173 |
NCT00000177 |
Estrogen Hormone Protocol |
Completed |
Estradiol |
Dec. 11, 2009 |
|
| 174 |
NCT00053599 |
Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease Study |
Completed |
Simvastatin |
July 28, 2009 |
|
| 175 |
NCT00056225 |
VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study) |
Completed |
Folic acid, Vitamin B6, Vitamin B12 |
June 12, 2009 |
|
| 176 |
NCT00105547 |
Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's |
Completed |
Tarenflurbil (MPC-7869) |
May 5, 2009 |
|
| 177 |
NCT00621647 |
Seroquel- Agitation Associated With Dementia |
Completed |
Quetiapine |
March 25, 2009 |
|
| 178 |
NCT00715858 |
A Pilot Study of Inflammatory Markers in Alzheimer's Disease |
Unknown status |
Doxycycline, Rifampicin |
Feb. 4, 2009 |
|
| 179 |
NCT00103649 |
18-Month Study of the Efficacy of Xaliproden (SR57746A) in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type |
Completed |
Xaliproden |
Aug. 21, 2008 |
|
| 180 |
NCT00104013 |
Study of Xaliproden (SR57746A) in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type |
Completed |
Xaliproden |
Aug. 21, 2008 |
|
| 181 |
NCT00322036 |
Global Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's |
Terminated |
Tarenflurbil (MPC-7869) |
Aug. 5, 2008 |
|
| 182 |
NCT00380276 |
Open-Label Treatment With MPC-7869 for Patients With Alzheimer's Who Previously Participated in an MPC-7869 Protocol |
Terminated |
Tarenflurbil (MPC-7869) |
Aug. 5, 2008 |
|
| 183 |
NCT00151502 |
To Evaluate the Safety and Effectiveness of Atorvastatin Plus a Cholinesterase Inhibitor in AD Patients. |
Completed |
Atorvastatin |
July 11, 2008 |
|
| 184 |
NCT00134953 |
Efficacy and Safety of Rivastigmine in Patients With Mild Cognitive Impairment |
Terminated |
Rivastigmine |
Dec. 17, 2007 |
|
| 185 |
NCT00217763 |
European Study of 3APS in Mild to Moderate Alzheimer's Disease Patients |
Unknown status |
Tramiprosate (3APS) |
Dec. 10, 2007 |
|
| 186 |
NCT00231946 |
ALADDIN Study - Phase III: Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation (VP-AD-301) |
Completed |
Leuprolide (VP4896) |
Sept. 20, 2007 |
|
| 187 |
NCT00314912 |
Open-Label Extension of the Phase III Study With Tramiprosate (3APS) in Patients With Mild to Moderate Alzheimer's Disease |
Unknown status |
Tramiprosate |
July 16, 2007 |
|
| 188 |
NCT00088673 |
Evaluation of 3APS in Patients With Mild to Moderate Alzheimer's Disease |
Unknown status |
Tramiprosate (3APS) |
Feb. 28, 2007 |
|
| 189 |
NCT00432081 |
Effect of Indomethacin on the Progression of Alzheimer's Disease |
Completed |
Indometacin |
Feb. 6, 2007 |
|
| 190 |
NCT00000171 |
Study of Melatonin: Sleep Problems in Alzheimer's Disease |
Completed |
Melatonin |
June 24, 2005 |
|
| 191 |
NCT00000172 |
Evaluation of Galantamine in the Treatment of Alzheimer's Disease |
Completed |
Galantamine |
June 24, 2005 |
|
| 192 |
NCT00000174 |
Investigation Into Delay to Diagnosis of Alzheimer's Disease With Exelon (InDDEx) |
Completed |
Rivastigmine |
June 24, 2005 |
|
| 193 |
NCT00000178 |
Multicenter Trial of Prednisone in Alzheimer's Disease |
Completed |
Prednisone |
June 24, 2005 |
|
| 194 |
NCT00000179 |
Agitation in Alzheimer's Disease |
Completed |
Trazodone, Haloperidol |
June 24, 2005 |
|
| # |
ID |
Title |
Status |
Agent |
Date updated |
Details |
| 1 |
NCT02292238 |
Benfotiamine in Alzheimer's Disease: A Pilot Study |
Active, not recruiting |
Benfotiamine |
July 16, 2020 |
|
| 2 |
NCT02720445 |
Memory Improvement Through Nicotine Dosing (MIND) Study |
Recruiting |
Nicotine |
July 14, 2020 |
|
| 3 |
NCT03977584 |
Tau Positron Emission Tomography (PET) Longitudinal Substudy Associated With: Study of Crenezumab Versus Placebo in Preclinical Presenilin1 (PSEN1) E280A Mutation Carriers in the Treatment of Autosomal-Dominant Alzheimer's Disease |
Recruiting |
Crenezumab |
July 14, 2020 |
|
| 4 |
NCT03461861 |
Network-Level Mechanisms for Preclinical Alzheimer's Disease Development |
Suspended |
AGB101 |
July 13, 2020 |
|
| 5 |
NCT04032626 |
MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients |
Recruiting |
Lenalidomide |
July 13, 2020 |
|
| 6 |
NCT04263519 |
A Pilot Open Labeled Study of Tacrolimus in Alzheimer's Disease. |
Not yet recruiting |
Tacrolimus |
July 13, 2020 |
|
| 7 |
NCT04311515 |
To Evaluate Safety, Tolerability and Pharmacological Effects of PU AD in Subjects With Mild AD Dementia |
Recruiting |
PU-AD |
July 13, 2020 |
|
| 8 |
NCT02792257 |
Trial of Dronabinol Adjunctive Treatment of Agitation in Alzheimer's Disease (AD) (THC-AD) |
Recruiting |
Dronabinol |
July 10, 2020 |
|
| 9 |
NCT03184467 |
Clinical Trial to Evaluate the Efficacy and Safety of GV1001 in Alzheimer Patients |
Completed |
GV1001 |
July 9, 2020 |
|
| 10 |
NCT03518073 |
A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease |
Active, not recruiting |
LY3303560 |
July 7, 2020 |
|
| 11 |
NCT03625622 |
Efficacy and Safety of 26-Week Treatment of AR1001 in Patients With Mild to Moderate Alzheimer's Disease |
Active, not recruiting |
AR1001 |
July 7, 2020 |
|
| 12 |
NCT03856359 |
Trial of Rifaximin in Probable Alzheimer's Disease |
Active, not recruiting |
Rifaximin |
July 7, 2020 |
|
| 13 |
NCT03867253 |
Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease |
Active, not recruiting |
ORY-2001 |
July 7, 2020 |
|
| 14 |
NCT04437511 |
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2) |
Not yet recruiting |
Donanemab |
July 7, 2020 |
|
| 15 |
NCT02406027 |
An Extension Study to Evaluate the Long-Term Safety and Tolerability of JNJ-54861911 in Participants in the Early Alzheimer's Disease Spectrum |
Terminated |
Atabecestat (JNJ-54861911) |
June 30, 2020 |
|
| 16 |
NCT03538522 |
A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831 |
Completed |
Traneurocin |
June 30, 2020 |
|
| 17 |
NCT04251182 |
Clinical Study Evaluating Efficacy and Safety of T3D-959 in Mild-to-moderate AD Subjects |
Suspended |
T3D-959 |
June 29, 2020 |
|
| 18 |
NCT03289143 |
A Study to Evaluate the Efficacy and Safety of Semorinemab in Patients With Prodromal to Mild Alzheimer's Disease |
Active, not recruiting |
Semorinemab |
June 24, 2020 |
|
| 19 |
NCT04436081 |
Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease |
Not yet recruiting |
Cannabidiol |
June 17, 2020 |
|
| 20 |
NCT03507790 |
A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease. |
Active, not recruiting |
CT1812 |
June 16, 2020 |
|
| 21 |
NCT03919162 |
A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD |
Not yet recruiting |
PQ912 |
June 16, 2020 |
|
| 22 |
NCT03828747 |
A Study of Semorinemab in Patients With Moderate Alzheimer's Disease |
Recruiting |
Semorinemab |
June 9, 2020 |
|
| 23 |
NCT02185053 |
A Phase II Study of CPC-201 to Treat Alzheimer's Disease Type Dementia |
Completed |
Donepezil, Solifenacin |
June 4, 2020 |
|
| 24 |
NCT03001557 |
Study of Lemborexant for Irregular Sleep-Wake Rhythm Disorder and Mild to Moderate Alzheimer's Disease Dementia |
Completed |
Lemborexant |
June 1, 2020 |
|
| 25 |
NCT03649724 |
The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's |
Recruiting |
Leuprolide |
May 28, 2020 |
|
| 26 |
NCT00876863 |
Randomized, Controlled Study Evaluating CERE-110 in Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
CERE-110 |
May 21, 2020 |
|
| 27 |
NCT03765762 |
A Study to Assess the Safety of GRF6019 Infusions in Subjects With Severe Alzheimer's Disease |
Completed |
GRF6019 |
May 21, 2020 |
|
| 28 |
NCT02788513 |
BI 425809 in Patients With Cognitive Impairment Due to Alzheimer's Disease. |
Completed |
BI 425809 |
May 19, 2020 |
|
| 29 |
NCT04388254 |
PTI-125, 100 mg, for Mild-to-moderate Alzheimer's Disease Patients |
Recruiting |
PTI-125 |
May 14, 2020 |
|
| 30 |
NCT04079803 |
PTI-125 for Mild-to-moderate Alzheimer's Disease Patients |
Completed |
PTI-125 |
May 12, 2020 |
|
| 31 |
NCT02380573 |
Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease |
Suspended |
Methylene blue, Brillant Blue FCF, Phenazopyridine |
May 11, 2020 |
|
| 32 |
NCT01998841 |
A Study of Crenezumab Versus Placebo in Preclinical Presenilin1 (PSEN1) E280A Mutation Carriers to Evaluate Efficacy and Safety in the Treatment of Autosomal-Dominant Alzheimer's Disease (AD), Including a Placebo-Treated Non-Carrier Cohort |
Active, not recruiting |
Crenezumab |
May 7, 2020 |
|
| 33 |
NCT03462121 |
A Clinical Study Evaluating the Efficacy and Safety of RPh201 Treatment in Individuals With Alzheimer's Disease With or Without Coexisting Cerebrovascular Disease |
Completed |
RPh201 |
April 30, 2020 |
|
| 34 |
NCT02129348 |
Treatment of Psychosis and Agitation in Alzheimer's Disease |
Completed |
Lithium cation |
April 29, 2020 |
|
| 35 |
NCT02910102 |
Study Evaluating Intepirdine (RVT-101) on Gait and Balance in Subjects With Dementia |
Completed |
Intepirdine (RVT-101) |
April 28, 2020 |
|
| 36 |
NCT03639987 |
A Study of Aducanumab in Participants With Mild Cognitive Impairment Due to Alzheimer's Disease or With Mild Alzheimer's Disease Dementia to Evaluate the Safety of Continued Dosing in Participants With Asymptomatic Amyloid-Related Imaging Abnormalities |
Terminated |
Aducanumab |
April 24, 2020 |
|
| 37 |
NCT03875638 |
Treating Hyperexcitability in AD With Levetiracetam |
Active, not recruiting |
Levetiracetam |
April 24, 2020 |
|
| 38 |
NCT02085265 |
Telmisartan vs. Perindopril in Mild-Moderate Alzheimer's Disease Patients |
Recruiting |
Telmisartan, Perindopril |
April 20, 2020 |
|
| 39 |
NCT03533257 |
Study to Assess the Safety and Biological Activity of AMX0035 for the Treatment of Alzheimer's Disease |
Active, not recruiting |
Phenylbutyric acid, Tauroursodeoxycholic acid |
April 20, 2020 |
|
| 40 |
NCT02503501 |
Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer's Disease |
Terminated |
Insulin Glulisine |
April 9, 2020 |
|
| 41 |
NCT02727699 |
A Phase II Study to Assess the Safety, Tolerability and Efficacy of Xanamem™ in Subjects With Mild Dementia Due to AD (XanADu) |
Completed |
Xanamem |
April 9, 2020 |
|
| 42 |
NCT03118947 |
A Study of Pimavanserin for the Treatment of Agitation and Aggression in Subjects With Alzheimer's Disease |
Completed |
Pimavanserin |
April 9, 2020 |
|
| 43 |
NCT02997982 |
Feasibility and Effects of Valaciclovir Treatment in Persons With Early Alzheimer's Disease |
Completed |
Valaciclovir |
April 3, 2020 |
|
| 44 |
NCT03489044 |
An Investigation of Levetiracetam in Alzheimer's Disease |
Active, not recruiting |
Levetiracetam |
March 27, 2020 |
|
| 45 |
NCT03625401 |
Efficacy and Safety of AD-35 in Treatment of Subjects With Mild to Moderate Alzheimer's Disease |
Active, not recruiting |
AD-35 |
March 25, 2020 |
|
| 46 |
NCT03710642 |
Prazosin for Agitation in Alzheimer's Disease |
Active, not recruiting |
Prazosin |
March 20, 2020 |
|
| 47 |
NCT03402503 |
Safety, and Efficacy of a New Buccal Film of Montelukast in Patients With Mild to Moderate Alzheimer's Disease |
Recruiting |
Montelukast |
March 19, 2020 |
|
| 48 |
NCT02551809 |
Evaluate the Safety, Tolerability, Immunogenicity and Efficacy of UB-311 in Mild Alzheimer's Disease (AD) Patients |
Completed |
UB-311 |
March 17, 2020 |
|
| 49 |
NCT01409915 |
Study of the Safety & Efficacy of Leukine® in the Treatment of Alzheimer's Disease |
Completed |
Sargramostim |
March 16, 2020 |
|
| 50 |
NCT04191486 |
Efficacy and Safety of T-817MA in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD |
Recruiting |
Edonerpic (T-817MA) |
March 12, 2020 |
|
| 51 |
NCT01767311 |
A Study to Evaluate Safety, Tolerability, and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease |
Active, not recruiting |
BAN-2401 |
Feb. 28, 2020 |
|
| 52 |
NCT02322021 |
Dose-Finding Study To Evaluate the Safety and Tolerability of E2609 in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease (Prodromal Alzheimer's Disease) and Mild to Moderate Dementia Due to Alzheimer's Disease |
Completed |
Elenbecestat |
Feb. 28, 2020 |
|
| 53 |
NCT02615002 |
Safety and Efficacy of Piromelatine in Mild Alzheimer's Disease Patients (ReCOGNITION) |
Completed |
Piromelatine |
Feb. 26, 2020 |
|
| 54 |
NCT03044249 |
A Study of MP-101 in Dementia-Related Psychosis and/or Agitation and Aggression |
Terminated |
MP-101 |
Feb. 26, 2020 |
|
| 55 |
NCT01723826 |
A Long-Term Safety Extension of Studies ABE4869g and ABE4955g in Participants With Mild to Moderate Alzheimer's Disease Treated With Crenezumab |
Completed |
Crenezumab |
Feb. 20, 2020 |
|
| 56 |
NCT04044131 |
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients |
Recruiting |
Metabolic Cofactor Supplementation, Sorbitol |
Feb. 13, 2020 |
|
| 57 |
NCT01097096 |
Safety, Tolerability and Abeta-specific Antibody Response of Repeated i.m. Injections of Adjuvanted CAD106 in Mild Alzheimer Patients |
Completed |
CAD106 |
Feb. 12, 2020 |
|
| 58 |
NCT00733863 |
Safety and Tolerability of Repeated Subcutaneous Injections of CAD106 in Mild Alzheimer's Patients. |
Completed |
CAD106 |
Feb. 11, 2020 |
|
| 59 |
NCT00956410 |
To Investigate the Safety and Tolerability of Repeated Subcutaneous Injections of CAD106 in Alzheimer's Patients |
Completed |
CAD106 |
Feb. 11, 2020 |
|
| 60 |
NCT03234686 |
Deferiprone to Delay Dementia (The 3D Study) |
Recruiting |
Deferiprone |
Feb. 11, 2020 |
|
| 61 |
NCT02646982 |
Candesartan's Effects on Alzheimer's Disease And Related Biomarkers |
Recruiting |
Candesartan cilexetil |
Feb. 10, 2020 |
|
| 62 |
NCT03352557 |
Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease |
Active, not recruiting |
Gosuranemab |
Feb. 7, 2020 |
|
| 63 |
NCT03367403 |
A Study of LY3002813 in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ) |
Active, not recruiting |
LY3002813 |
Feb. 5, 2020 |
|
| 64 |
NCT03712787 |
An Extension Study of ABBV-8E12 in Early Alzheimer's Disease (AD) |
Enrolling by invitation |
ABBV-8E12 |
Jan. 31, 2020 |
|
| 65 |
NCT01703117 |
Riluzole in Mild Alzheimer's Disease |
Active, not recruiting |
Riluzole |
Jan. 30, 2020 |
|
| 66 |
NCT01811381 |
Curcumin and Yoga Therapy for Those at Risk for Alzheimer's Disease |
Active, not recruiting |
Curcumin |
Jan. 28, 2020 |
|
| 67 |
NCT00205179 |
Alzheimer's Disease: Potential Benefit of Isoflavones |
Completed |
Soy isoflavones |
Jan. 22, 2020 |
|
| 68 |
NCT02880956 |
A Study to Evaluate the Efficacy and Safety of ABBV-8E12 in Subjects With Early Alzheimer's Disease |
Active, not recruiting |
ABBV-8E12 |
Jan. 18, 2020 |
|
| 69 |
NCT03282916 |
Anti-viral Therapy in Alzheimer's Disease |
Recruiting |
Valaciclovir |
Jan. 7, 2020 |
|
| 70 |
NCT00299988 |
Phase II Study of Intravenous Immunoglobulin (IVIg) for Alzheimer's Disease |
Terminated |
Intravenous Immunoglobulin |
Dec. 11, 2019 |
|
| 71 |
NCT03531710 |
An Extension Study of V203-AD Study to Evaluate the Safety, Tolerability, Immunogenicity, and Efficacy of UB-311 |
Terminated |
UB-311 |
Dec. 10, 2019 |
|
| 72 |
NCT02002819 |
Levetiracetam for Alzheimer's Disease-Associated Network Hyperexcitability |
Recruiting |
Levetiracetam |
Nov. 22, 2019 |
|
| 73 |
NCT02756858 |
An Extension Study of ANAVEX2-73 in Patients With Mild to Moderate Alzheimer's Disease |
Active, not recruiting |
ANAVEX2-73 |
Nov. 19, 2019 |
|
| 74 |
NCT02580305 |
SUVN-502 With Donepezil and Memantine for the Treatment of Moderate Alzheimer's Disease- Phase 2a Study |
Completed |
SUVN-502 |
Nov. 18, 2019 |
|
| 75 |
NCT02579252 |
24 Months Safety and Efficacy Study of AADvac1 in Patients With Mild Alzheimer's Disease |
Completed |
AADvac1 |
Nov. 14, 2019 |
|
| 76 |
NCT04070378 |
Study of Daratumumab in Patients With Mild to Moderate Alzheimer's Disease |
Recruiting |
Daratumumab |
Nov. 8, 2019 |
|
| 77 |
NCT00568776 |
ELND005 in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
scyllo-inositol (ELND005) |
Nov. 1, 2019 |
|
| 78 |
NCT03817684 |
Tetra PICASSO AD Trial: Study to Evaluate Effects of BPN14770 in Early Alzheimer's Subjects |
Active, not recruiting |
BPN14770 |
Oct. 31, 2019 |
|
| 79 |
NCT00934050 |
ELND005 Long-Term Follow-up Study in Subjects With Alzheimer's Disease |
Completed |
scyllo-inositol |
Oct. 21, 2019 |
|
| 80 |
NCT01735630 |
Efficacy and Safety Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease |
Completed |
scyllo-inositol |
Oct. 21, 2019 |
|
| 81 |
NCT01766336 |
A 36-Week Safety Extension Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease |
Terminated |
scyllo-inositol |
Oct. 21, 2019 |
|
| 82 |
NCT01300728 |
Study of Intravenous Immunoglobulin in Amnestic Mild Cognitive Impairment |
Active, not recruiting |
NewGam 10% IVIG |
Oct. 8, 2019 |
|
| 83 |
NCT02791191 |
A Study of LY3202626 on Disease Progression in Participants With Mild Alzheimer's Disease Dementia |
Terminated |
LY3202626 |
Oct. 8, 2019 |
|
| 84 |
NCT03402659 |
Proof-of-Concept Study of a Selective p38 MAPK Alpha Inhibitor, Neflamapimod, in Subjects With Mild Alzheimer's Disease |
Completed |
Neflamapimod |
Oct. 3, 2019 |
|
| 85 |
NCT03991988 |
Montelukast Therapy on Alzheimer's Disease |
Recruiting |
Montelukast |
Sept. 30, 2019 |
|
| 86 |
NCT03061474 |
Nicotinamide as an Early Alzheimer's Disease Treatment |
Recruiting |
Nicotinamide |
Sept. 26, 2019 |
|
| 87 |
NCT00751907 |
Cerebral and Peripheral Perfusion Pilot Study |
Completed |
Atorvastatin |
Sept. 9, 2019 |
|
| 88 |
NCT03062449 |
Phase IIa L-serine Trial for eAD |
Recruiting |
Serine |
Sept. 9, 2019 |
|
| 89 |
NCT03748706 |
PTI-125 for Mild-to-moderate Alzheimer's Disease Patients |
Completed |
PTI-125 |
Sept. 6, 2019 |
|
| 90 |
NCT03055741 |
Study of DHP1401 in Patients With Mild-moderate Alzheimer's Disease Treated With Donepezil(DRAMA) |
Completed |
Donepezil, DHP1401 |
Aug. 20, 2019 |
|
| 91 |
NCT03560245 |
A Study of Bryostatin in Moderately Severe to Severe Alzheimer's Disease Subjects Not On Memantine |
Completed |
Bryostatin 1 |
Aug. 20, 2019 |
|
| 92 |
NCT02167256 |
A Phase IIa Multi-Center Study of 18F-FDG PET, Safety, and Tolerability of AZD0530 in Mild Alzheimer's Disease |
Completed |
Saracatinib (AZD0530) |
Aug. 14, 2019 |
|
| 93 |
NCT04052737 |
PMZ-1620 (Sovateltide) in Mild to Moderate Alzheimer's Disease |
Recruiting |
PMZ-1620 |
Aug. 13, 2019 |
|
| 94 |
NCT00596024 |
Lutein and Alzheimer's Disease Study |
Terminated |
Lutein, Zeaxanthin |
Aug. 12, 2019 |
|
| 95 |
NCT00939822 |
Statin Effects on Beta-Amyloid and Cerebral Perfusion in Adults at Risk for Alzheimer's Disease |
Completed |
Simvastatin |
Aug. 9, 2019 |
|
| 96 |
NCT02467413 |
BAC in Patient With Alzheimer's Disease or Vascular Dementia |
Withdrawn |
BAC |
July 31, 2019 |
|
| 97 |
NCT01439555 |
Endothelial Facilitation in Alzheimer's Disease |
Completed |
Simvastatin, L-Arginine, Sapropterin |
July 30, 2019 |
|
| 98 |
NCT02886494 |
A Study to Evaluate Efficacy and Safety of BAC in Patient With Alzheimer's Disease or Vascular Dementia |
Completed |
BAC |
July 30, 2019 |
|
| 99 |
NCT01522404 |
Effects of Atomoxetine in Mild Cognitive Impairment |
Completed |
Atomoxetine |
July 23, 2019 |
|
| 100 |
NCT03613844 |
DHA Brain Delivery Trial |
Recruiting |
Doconexent |
July 19, 2019 |
|
| 101 |
NCT03520998 |
A Randomized Study to Assess the Safety of GRF6019 Infusions in Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
GRF6019 |
July 16, 2019 |
|
| 102 |
NCT03461276 |
Safety and Immunogenicity of Repeated Doses of ABvac40 in Patients With a-MCI or Vm-AD |
Recruiting |
ABvac40 |
July 5, 2019 |
|
| 103 |
NCT04004702 |
Levetiracetam for Alzheimer's Disease Neuropsychiatric Symptoms Related to Epilepsy Trial (LAPSE) |
Not yet recruiting |
Levetiracetam |
July 2, 2019 |
|
| 104 |
NCT03319810 |
Effect of IVIG on Cerebral and Retinal Amyloid in Mild Cognitive Impairment Due to Alzheimer Disease |
Completed |
Octagam |
June 25, 2019 |
|
| 105 |
NCT01953705 |
n-3 PUFA for Vascular Cognitive Aging |
Active, not recruiting |
Omega-3 fatty acids |
June 17, 2019 |
|
| 106 |
NCT02423122 |
A PET Study of the Effects of p38 MAP Kinase Inhibitor, VX-745, on Amyloid Plaque Load in Alzheimer's Disease (AD) |
Completed |
Neflamapimod (VX-745) |
June 14, 2019 |
|
| 107 |
NCT01843075 |
Evaluating Liraglutide in Alzheimer's Disease |
Active, not recruiting |
Liraglutide |
June 10, 2019 |
|
| 108 |
NCT03363269 |
Evaluate the Efficacy and Safety of ID1201 for Dose-finding in Mild Alzheimer's Disease |
Completed |
ID1201 |
June 4, 2019 |
|
| 109 |
NCT03959553 |
GV1001 Subcutaneous(SC) for the Treatment of Moderate Alzheimer's Disease (AD) |
Not yet recruiting |
GV1001 |
May 28, 2019 |
|
| 110 |
NCT03531684 |
Efficacy and Safety of MMFS in Early AD |
Recruiting |
MMFS-205-SR |
May 22, 2019 |
|
| 111 |
NCT02359552 |
Rasagiline Rescue in Alzheimer's Disease Clinical Trial |
Completed |
Rasagiline |
May 8, 2019 |
|
| 112 |
NCT02833792 |
Allogeneic Human Mesenchymal Stem Cells for Alzheimer's Disease |
Recruiting |
Human Mesenchymal Stem Cells |
April 9, 2019 |
|
| 113 |
NCT02500784 |
Improving Beta-2 Adrenergic Signaling in Alzheimer's Disease |
Suspended |
Formoterol |
April 3, 2019 |
|
| 114 |
NCT02992132 |
Study to Examine the Safety and Efficacy of Pimavanserin for the Treatment of Agitation and Aggression in Alzheimer's Disease (SERENE) |
Terminated |
Pimavanserin |
March 28, 2019 |
|
| 115 |
NCT02033941 |
Phase 2 Study to Examine Grape Seed Extract as an Anti-Oligomerization Agent in Alzheimer's Disease (AD) |
Recruiting |
Meganatural-Az Grapeseed Extract |
March 13, 2019 |
|
| 116 |
NCT02947893 |
Impact of Nilotinib on Safety, Biomarkers and Clinical Outcomes in Mild to Moderate Alzheimer's Disease |
Active, not recruiting |
Nilotinib |
March 13, 2019 |
|
| 117 |
NCT00486044 |
Evaluating Simvastatin's Potential Role in Therapy |
Completed |
Simvastatin |
March 5, 2019 |
|
| 118 |
NCT02549196 |
A Dose Titration Study of CPC-201 in Patients With Dementia of Alzheimer's Type |
Completed |
Donepezil, Solifenacin |
March 5, 2019 |
|
| 119 |
NCT03417986 |
Clinical Trial to Explore the the Amyloid Beta Draining Effect of Thiethylperazine (TEP) in Subjects With Newly Diagnosed Early-to-mild Dementia Due to Alzheimer's Disease (AD) in Comparison to Healthy Volunteers |
Active, not recruiting |
Thiethylperazine |
Feb. 27, 2019 |
|
| 120 |
NCT02079909 |
Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease (US202) |
Completed |
Edonerpic (T-817MA) |
Feb. 26, 2019 |
|
| 121 |
NCT00814346 |
Effect of EGb761® on Brain Glucose Metabolism in Three Groups of Elderly Defined by Cognitive Functions |
Completed |
Ginkgo biloba |
Feb. 8, 2019 |
|
| 122 |
NCT03806478 |
Study of APH-1105 in Patients With Mild to Moderate Alzheimer's Disease |
Not yet recruiting |
APH-1105 |
Jan. 16, 2019 |
|
| 123 |
NCT03790982 |
Evaluate the Safety and Efficacy of AD-35 Tablet in Subjects With Mild to Moderate Alzheimer's Disease |
Active, not recruiting |
AD-35 |
Jan. 2, 2019 |
|
| 124 |
NCT03250741 |
Effects of Dopaminergic Therapy in Patients With Alzheimer's Disease |
Completed |
Rotigotine |
Dec. 17, 2018 |
|
| 125 |
NCT00976118 |
Activity of Masitinib (AB1010) in Mild to Moderate Alzheimer's Disease |
Completed |
Masitinib |
Dec. 13, 2018 |
|
| 126 |
NCT00566397 |
A Phase 2 Study Evaluating The Efficacy And Safety Of PF 04494700 In Mild To Moderate Alzheimer's Disease |
Completed |
Azeliragon (PF-04494700) |
Nov. 30, 2018 |
|
| 127 |
NCT02240693 |
Alzheimer Disease Proof of Concept Study With BI 409306 Versus Placebo |
Completed |
BI 409306 |
Nov. 28, 2018 |
|
| 128 |
NCT02244541 |
Phase 2a Dose Finding, PK/PD and 12 Month Exploratory Efficacy Study of ANAVEX2-73 in Patients With Alzheimer's Disease |
Completed |
ANAVEX2-73 |
Nov. 28, 2018 |
|
| 129 |
NCT03752463 |
NMDA Enhancer for the Treatment of Mild Alzheimer's Disease |
Unknown status |
DAOI |
Nov. 26, 2018 |
|
| 130 |
NCT03435861 |
Effect of Neflamapimod on Brain Inflammation in Alzheimer's Disease Patients |
Recruiting |
Neflamapimod (VX-745) |
Nov. 21, 2018 |
|
| 131 |
NCT02337907 |
BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease. |
Completed |
Donepezil, BI 409306 |
Nov. 14, 2018 |
|
| 132 |
NCT02064920 |
Computerized Cognition Testing in Participants With Mild Alzheimer's Disease (AD) Treated With Donepezil (MK-0000-318) |
Completed |
Donepezil |
Oct. 12, 2018 |
|
| 133 |
NCT01428453 |
A Phase 2a Study to Evaluate the Effect of Rilapladib (SB-659032) in Alzheimer's Disease |
Completed |
Rilapladib |
Sept. 24, 2018 |
|
| 134 |
NCT01852110 |
Efficacy and Safety of MK-7622 as Adjunct Therapy in Participants With Alzheimer's Disease (MK-7622-012) |
Terminated |
MK-7622, AChEI |
Sept. 18, 2018 |
|
| 135 |
NCT03656042 |
To Evaluate the Efficacy and Safety/Tolerability Profiles of G-CSF in Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
Filgrastim |
Sept. 4, 2018 |
|
| 136 |
NCT02626572 |
Efficacy and Safety of 3 Doses of S47445 Versus Placebo in Patients With Alzheimer's Disease at Mild to Moderate Stages With Depressive Symptoms |
Completed |
S47445 |
Aug. 15, 2018 |
|
| 137 |
NCT00708552 |
Study of SB-742457 or Donepezil Versus Placebo in Subjects With Mild-to-moderate Alzheimer's Disease |
Completed |
Intepirdine (SB-742457), Donepezil |
July 27, 2018 |
|
| 138 |
NCT00040443 |
Efficacy And Safety Of CX516 In Elderly Participants With Mild Cognitive Impairment. |
Completed |
CX516 |
July 23, 2018 |
|
| 139 |
NCT02431468 |
A Study Assessing Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer's Disease |
Completed |
Bryostatin 1 |
July 6, 2018 |
|
| 140 |
NCT01117181 |
Apathy in Dementia Methylphenidate Trial (ADMET) |
Completed |
Methylphenidate |
June 12, 2018 |
|
| 141 |
NCT01018875 |
Efficacy and Safety Study of ABT-288 in Subjects With Mild-to-Moderate Alzheimer's Disease |
Completed |
ABT-288, Donepezil |
June 6, 2018 |
|
| 142 |
NCT00940589 |
Efficacy of Circadin® 2 mg in Patients With Mild to Moderate Alzheimer Disease Treated With AChE Inhibitor |
Completed |
Melatonin |
June 1, 2018 |
|
| 143 |
NCT01595646 |
Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 120 Days (SL120) |
Completed |
Insulin Detemir |
May 22, 2018 |
|
| 144 |
NCT00684944 |
Open Label Study of TRx0014 in Alzheimer's Disease |
Completed |
Methylene blue (TRx0014) |
April 27, 2018 |
|
| 145 |
NCT02423200 |
Clinical Pharmacology of p38 MAP Kinase Inhibitor, VX-745, in Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD |
Completed |
Neflamapimod (VX-745) |
April 3, 2018 |
|
| 146 |
NCT01255163 |
A Pilot Clinical Trial of Exendin-4 in Alzheimer's Disease |
Terminated |
Exenatide |
Feb. 22, 2018 |
|
| 147 |
NCT02471196 |
Efficacy of ORM-12741 on Agitation/Aggression Symptoms in Alzheimer's Disease |
Completed |
ORM-12741 |
Feb. 15, 2018 |
|
| 148 |
NCT01078168 |
Alzheimer`s Disease Acitretin Medication |
Completed |
Acitretin |
Feb. 5, 2018 |
|
| 149 |
NCT02103673 |
DAOIB for the Treatment of Cognitive Function and Behavioral and Psychological Symptoms of Dementia |
Completed |
DAOIB |
Jan. 24, 2018 |
|
| 150 |
NCT01584440 |
Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Alzheimer's Patients |
Completed |
Dextromethorphan, Quinidine |
Jan. 11, 2018 |
|
| 151 |
NCT00710684 |
A Study of SB-742457, Added to Donepezil for the Treatment of Mild-to-moderate Alzheimer's Disease |
Completed |
Intepirdine (SB-742457), Donepezil |
Dec. 7, 2017 |
|
| 152 |
NCT00843518 |
Treatment for Aggression and Agitation in Patients With Alzheimer's Disease |
Completed |
Mibampator (LY451395) |
Nov. 29, 2017 |
|
| 153 |
NCT02035553 |
A Study of the Safety and Efficacy of Pimavanserin in Patients With Alzheimer's Disease Psychosis |
Completed |
Pimavanserin |
Oct. 25, 2017 |
|
| 154 |
NCT01965756 |
Effect of Insulin Sensitizer Metformin on AD Biomarkers |
Completed |
Metformin |
Sept. 21, 2017 |
|
| 155 |
NCT02434666 |
Long Term Extension Safety Study in Patients With Dementia of the Alzheimer's Type Who Completed Study CPC-001-07 |
Completed |
Donepezil, Solifenacin |
Sept. 20, 2017 |
|
| 156 |
NCT01044758 |
Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI) |
Completed |
Levetiracetam |
Aug. 21, 2017 |
|
| 157 |
NCT00325728 |
Efficacy and Safety of Ramelteon in Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
Ramelteon |
Aug. 14, 2017 |
|
| 158 |
NCT02576639 |
Dose-ranging Safety and Tolerability Study in Subjects ≥60 Years of Age |
Completed |
CNP520 |
Aug. 11, 2017 |
|
| 159 |
NCT02860065 |
CPC-201 Alzheimer's Disease Type Dementia: PET Study |
Withdrawn |
Donepezil, Solifenacin |
Aug. 9, 2017 |
|
| 160 |
NCT02702817 |
Randomized Trial of Low-dose Naproxen in Cognitively Intact Persons at Risk of Alzheimer's Dementia |
Completed |
Naproxen |
Aug. 1, 2017 |
|
| 161 |
NCT01343966 |
A Study to Evaluate the Efficacy and Safety of MABT5102A in Patients With Mild to Moderate Alzheimer's Disease (ABBY) |
Completed |
Crenezumab (MABT5102A) |
July 12, 2017 |
|
| 162 |
NCT01397578 |
A Study to Evaluate the Impact of MABT5102A on Brain Amyloid Load and Related Biomarkers in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
Crenezumab (MABT5102A) |
July 12, 2017 |
|
| 163 |
NCT01429623 |
A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment |
Completed |
Ladostigil hemitartrate |
June 15, 2017 |
|
| 164 |
NCT00916617 |
Study Evaluating The Long-Term Safety And Efficacy Of Subcutaneous Bapineuzumab |
Terminated |
Bapineuzumab |
June 1, 2017 |
|
| 165 |
NCT02389413 |
Safety and Tolerability of PQ912 in Subjects With Early Alzheimer's Disease |
Completed |
PQ912 |
June 1, 2017 |
|
| 166 |
NCT01677754 |
A Study of RO4602522 in Participants With Moderate Severity Alzheimer Disease on Background Alzheimer Disease Therapy |
Completed |
RO4602522, Donepezil, Memantine, Rivastigmine, Galantamine |
May 30, 2017 |
|
| 167 |
NCT00381238 |
Open-Label Extension Assessing Long-Term Safety Of Rosiglitazone In Subjects With Mild To Moderate Alzheimer's Disease |
Completed |
Rosiglitazone |
May 23, 2017 |
|
| 168 |
NCT01009255 |
Study to Evaluate the Efficacy and Safety of GSK239512 in Alzheimer's Disease |
Completed |
GSK-239512 |
April 13, 2017 |
|
| 169 |
NCT02667496 |
Safety Study of Sargramostim in Treating Patients With Mild Cognitive Impairment Due to Alzheimer's Disease |
Withdrawn |
Sargramostim, Florbetapir (18F) |
April 7, 2017 |
|
| 170 |
NCT02279511 |
ATP in Alzheimer Disease |
Completed |
ATP |
March 29, 2017 |
|
| 171 |
NCT01712074 |
Study Evaluating TheSafety And Efficacy Of PF-05212377 Or Placebo In Subjects With Alzheimer's Disease With Existing Neuropsychiatric Symptoms On Donepezil |
Terminated |
PF-05212377 (SAM-760) |
March 20, 2017 |
|
| 172 |
NCT02260674 |
A Safety and Tolerability Study of JNJ-54861911 in Participants With Early Alzheimer's Disease |
Completed |
Atabecestat (JNJ-54861911) |
March 3, 2017 |
|
| 173 |
NCT01548287 |
A Study of the Safety and Tolerability of AZD5213 Effect on Sleep for Patients With Alzheimer's/Cognitive Impairment |
Completed |
AZD5213 |
Feb. 7, 2017 |
|
| 174 |
NCT03038035 |
The Alzheimer's Disease THErapy With NEuroaid (ATHENE) Study |
Unknown status |
MLC901 |
Jan. 31, 2017 |
|
| 175 |
NCT00470418 |
Development of NIC5-15 in the Treatment of Alzheimer's Disease |
Completed |
Methylinositol |
Jan. 9, 2017 |
|
| 176 |
NCT00265148 |
Brain Imaging Study Of Rosiglitazone Efficacy And Safety In Alzheimer's Disease |
Completed |
Rosiglitazone |
Nov. 16, 2016 |
|
| 177 |
NCT00884507 |
A Study of RO5313534 as Add-on to Donepezil Treatment in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
Facinicline |
Nov. 2, 2016 |
|
| 178 |
NCT01928420 |
A Single Site, Randomized, Double-blind, Placebo Controlled Trial of NIC5-15 in Subjects With Alzheimer's Disease |
Completed |
NIC5-15 |
Oct. 17, 2016 |
|
| 179 |
NCT00742417 |
Efficacy and Safety of Plasma Exchange With 5% Albumin in Beta-amyloid Peptide Clearance in Cerebral Spinal Fluid |
Completed |
Albumin |
June 14, 2016 |
|
| 180 |
NCT01504854 |
Resveratrol for Alzheimer's Disease |
Completed |
Resveratrol |
June 14, 2016 |
|
| 181 |
NCT00362024 |
MK0952 in Patients With Mild-to-Moderate Alzheimer's Disease (0952-004)(COMPLETED) |
Terminated |
MK0952 |
May 16, 2016 |
|
| 182 |
NCT00722046 |
Multiple IV Dose Study Of PF-04360365 In Patients With Mild To Moderate Alzheimer's Disease |
Completed |
Ponezumab (PF-04360365) |
May 5, 2016 |
|
| 183 |
NCT00945672 |
A Multiple Dose Study of PF-04360365 In Patients With Mild to Moderate Alzheimer's Disease |
Completed |
Ponezumab (PF-04360365) |
May 5, 2016 |
|
| 184 |
NCT01388478 |
Safety Study of R(+)Pramipexole to Treat Early Alzheimer's Disease |
Completed |
Pramipexole |
April 25, 2016 |
|
| 185 |
NCT00582855 |
Effect of AQW051 in Patients With Memory Impairment |
Terminated |
AQW051 |
April 19, 2016 |
|
| 186 |
NCT01715350 |
Study to Explore the Optimal Dosage/Administration in Alzheimer's Disease |
Completed |
PM012 |
April 18, 2016 |
|
| 187 |
NCT00960531 |
A Long Term Extension Study Evaluating ACC-001 With QS-21 in Subjects With Mild to Moderate Alzheimer's Disease |
Terminated |
Vanutide cridificar, QS-21 |
April 1, 2016 |
|
| 188 |
NCT01266525 |
Effect of Different Doses of SAR110894 on Cognition in Patients With Mild to Moderate Alzheimer's Disease on Donepezil |
Completed |
SAR110894, Donepezil |
March 14, 2016 |
|
| 189 |
NCT01320527 |
A Clinical Trial of a Vitamin/Nutriceutical Formulation for Alzheimer's Disease |
Completed |
Nutriceutical formulation |
March 3, 2016 |
|
| 190 |
NCT01227564 |
Amyloid Imaging And Safety Study Of ACC-001 In Subjects With Early Alzheimer's Disease |
Completed |
Vanutide cridificar, QS-21 |
Feb. 25, 2016 |
|
| 191 |
NCT02361242 |
24-week Open-label Extension Study Evaluating PXT00864 Effect in Mild AD Patients Further to PLEODIAL-I Completion |
Completed |
Baclofen, Acamprosate |
Feb. 15, 2016 |
|
| 192 |
NCT02361424 |
Pilot Study Assessing the Effects of PXT00864 in Patients With Mild Alzheimer Disease (AD) |
Completed |
Baclofen, Acamprosate |
Feb. 15, 2016 |
|
| 193 |
NCT01782742 |
Bexarotene Amyloid Treatment for Alzheimer's Disease |
Completed |
Bexarotene |
Feb. 12, 2016 |
|
| 194 |
NCT01303744 |
Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 |
Completed |
CHF 5074 |
Jan. 11, 2016 |
|
| 195 |
NCT00479557 |
Study Evaluating Safety, Tolerability, And Immunogenicity Of ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease |
Completed |
Vanutide cridificar, QS-21 |
Jan. 1, 2016 |
|
| 196 |
NCT00498602 |
Study Evaluating ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease |
Completed |
Vanutide cridificar, QS-21 |
Jan. 1, 2016 |
|
| 197 |
NCT00752232 |
Study Evaluating ACC-001 in Japanese Patients With Mild To Moderate Alzheimer's Disease |
Completed |
Vanutide cridificar, QS-21 |
Jan. 1, 2016 |
|
| 198 |
NCT00959192 |
Safety, Tolerability, And Immunogenicity Study Of ACC-001 In Japanese Subjects With Mild To Moderate Alzheimer's Disease |
Completed |
Vanutide cridificar, QS-21 |
Jan. 1, 2016 |
|
| 199 |
NCT00704782 |
Study of Combination Therapy With Dimebon and Donepezil (Aricept) in Patients With Alzheimer's Disease |
Terminated |
Latrepirdine |
Dec. 10, 2015 |
|
| 200 |
NCT00377715 |
Double-blind, Placebo-controlled Study of Oral Dimebon in Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
Latrepirdine |
Nov. 11, 2015 |
|
| 201 |
NCT01436045 |
Safety and Effectiveness Study of Intranasal Insulin Glulisine on Cognitive and Memory in Mild-Mod AD Patients. |
Completed |
Insulin Glulisine |
Oct. 19, 2015 |
|
| 202 |
NCT02246075 |
Study of the Safety of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease Currently Receiving Memantine |
Withdrawn |
Encenicline (EVP-6124) |
Oct. 15, 2015 |
|
| 203 |
NCT00810147 |
A Phase II, Multicenter, Double Blind, Placebo-Controlled Safety, Tolerability Study of BMS-708163 in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
Avagacestat (BMS-708163) |
Oct. 12, 2015 |
|
| 204 |
NCT00890890 |
A Multicenter, Double Blind, Placebo-Controlled, Safety and Tolerability Study of BMS-708163 in Patients With Prodromal Alzheimer's Disease |
Terminated |
Avagacestat |
Oct. 12, 2015 |
|
| 205 |
NCT01764243 |
Safety and Efficacy of MT-4666 |
Completed |
Encenicline (MT-4666) |
Sept. 28, 2015 |
|
| 206 |
NCT00074529 |
Study of MK0677 for the Treatment of Alzheimer's Disease (0677-030)(COMPLETED) |
Completed |
MK0677 |
July 24, 2015 |
|
| 207 |
NCT02008513 |
Follow-up Study to Assess Safety and Clinical Activity of Continued AFFITOPE® AD02 Vaccinations of Patients Who Participated in AFF006 |
Terminated |
AFFITOPE AD02 |
June 24, 2015 |
|
| 208 |
NCT01466088 |
Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD) |
Completed |
Donepezil |
June 3, 2015 |
|
| 209 |
NCT00012857 |
Pain Management and Behavioral Outcomes in Patients With Dementia |
Completed |
Acetaminophen |
April 7, 2015 |
|
| 210 |
NCT00368459 |
Raloxifene for Women With Alzheimer's Disease |
Completed |
Raloxifene |
April 2, 2015 |
|
| 211 |
NCT00420420 |
MK0249 for the Symptomatic Treatment of Alzheimer's Disease (MK0249-011) |
Completed |
MK-0249 |
Feb. 12, 2015 |
|
| 212 |
NCT01723670 |
Evaluation of Effects of Multiple Dose Regimens of CHF 5074 on Potential Biomarkers of Neurodegeneration in Subjects With Mild Cognitive Impairment |
Withdrawn |
CHF 5074 |
Feb. 10, 2015 |
|
| 213 |
NCT01453569 |
Safety, Efficacy and Dose Titration of Sodium Oligo-mannurarate Capsule on Mild to Moderate Alzheimer's Disease |
Completed |
Sodium oligo-mannurarate |
Jan. 27, 2015 |
|
| 214 |
NCT01284387 |
Amyloid Imaging And Safety Study Of ACC-001 In Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
Vanutide cridificar |
Jan. 5, 2015 |
|
| 215 |
NCT01238991 |
Long Term Extension Study Evaluating Safety, Tolerability And Immunogenicity Of ACC-001 In Japanese Subjects With Mild To Moderate Alzheimer's Disease |
Terminated |
Vanutide cridificar |
Dec. 22, 2014 |
|
| 216 |
NCT01527916 |
Evaluate the Efficacy and Safety of ABT-126 in Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
ABT-126, Donepezil |
Nov. 19, 2014 |
|
| 217 |
NCT01374438 |
3-month Study of MSDC-0160 Effects on Brain Glucose Utilization, Cognition & Safety in Subjects With Alzheimer's Disease |
Completed |
Mitoglitazone (MSDC-0160) |
Nov. 18, 2014 |
|
| 218 |
NCT01549834 |
Evaluate the Efficacy and Safety of ABT-126 in Subjects With Mild to Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors |
Completed |
ABT-126 |
Oct. 31, 2014 |
|
| 219 |
NCT01324518 |
Safety and Efficacy of ORM-12741 in Patients With Alzheimer's Disease |
Completed |
ORM-12741 |
Oct. 21, 2014 |
|
| 220 |
NCT02249351 |
Efficacy and Safety of Talsaclidine (Free Base) in Patients With Mild to Moderate Dementia of Alzheimer Type |
Terminated |
Talsaclidine |
Sept. 26, 2014 |
|
| 221 |
NCT02249403 |
Efficacy and Safety of Talsaclidine in Patients With Mild to Moderate Dementia of Alzheimer Type |
Completed |
Talsaclidine |
Sept. 26, 2014 |
|
| 222 |
NCT01463384 |
Minocycline in Patients With Alzheimer's Disease |
Completed |
Minocycline |
Sept. 25, 2014 |
|
| 223 |
NCT01255046 |
Study of STA-1 as an Add-on Treatment to Donepezil |
Unknown status |
Donepezil |
Aug. 20, 2014 |
|
| 224 |
NCT01276353 |
A Study Versus E2020 10mg Followed by an Open-label Extension Phase to Explore the Safety of E2020 SR 23 mg in Japanese Subjects With Severe Alzheimer's Type Dementia |
Completed |
Donepezil |
Aug. 8, 2014 |
|
| 225 |
NCT00501111 |
Proof of Concept Study of Cognitive Improvement in Patients With Alzheimer's Disease |
Completed |
AZD3480, Donepezil |
July 23, 2014 |
|
| 226 |
NCT01626391 |
Safety Study of TRx0237 in Patients Already Taking Medications for Mild and Moderate Alzheimer's Disease |
Terminated |
TRx0237 |
July 11, 2014 |
|
| 227 |
NCT01254773 |
Amyloid Imaging And Safety Study Of Subcutaneous Bapineuzumab In Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
Bapineuzumab |
May 9, 2014 |
|
| 228 |
NCT00812565 |
Study of Octagam (Intravenous Immunoglobulin [IVIG]) 10% on the Treatment of Mild to Moderate Alzheimer's Disease |
Completed |
Human immunoglobulin G |
May 5, 2014 |
|
| 229 |
NCT01073228 |
Safety and Cognitive Function Study of EVP-6124 in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
Encenicline (EVP-6124) |
April 25, 2014 |
|
| 230 |
NCT01068353 |
Safety and Tolerability of Etanercept in Alzheimer's Disease |
Completed |
Etanercept |
April 23, 2014 |
|
| 231 |
NCT01676935 |
This is a Safety and Tolerability Study Evaluating a New Treatment for Subjects With Mild to Moderate Alzheimer's Disease |
Terminated |
ABT-126 |
March 26, 2014 |
|
| 232 |
NCT01690195 |
Safety and Tolerability Study Evaluating a New Treatment for Subjects With Mild to Moderate Alzheimer's Disease |
Terminated |
ABT-126 |
March 26, 2014 |
|
| 233 |
NCT00073658 |
Treating Behavioral Disturbances in Individuals With Dementia |
Completed |
Citalopram, Risperidone |
March 10, 2014 |
|
| 234 |
NCT01075763 |
A Pilot Trial of Interferon Beta-1a in Alzheimer's Disease |
Completed |
Interferon beta-1a |
Feb. 13, 2014 |
|
| 235 |
NCT01421056 |
Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Open Label Extension (CT04 OLEP) |
Completed |
CHF 5074 |
Feb. 6, 2014 |
|
| 236 |
NCT01602393 |
Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Prolonged Open Label Extension Phase |
Completed |
CHF 5074 |
Feb. 6, 2014 |
|
| 237 |
NCT00955409 |
Long Term Extension Study Evaluating Safety, Tolerability and Immunogenicity Of ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease |
Completed |
Vanutide cridificar, QS-21 |
Jan. 31, 2014 |
|
| 238 |
NCT01661673 |
Safety, Tolerability, Pharmacokinetics of EVP-0962 and Effects of EVP-0962 on Cerebral Spinal Fluid Amyloid Concentrations in Healthy Subjects and in Subjects With Mild Cognitive Impairment or Early Alzheimer's Disease |
Completed |
EVP-0962 |
Jan. 13, 2014 |
|
| 239 |
NCT00257712 |
SMART: Somatotrophics, Memory, and Aging Research Trial |
Completed |
Tesamorelin (TH9507) |
Dec. 19, 2013 |
|
| 240 |
NCT01117818 |
Clinical- and Immunological Activity, Safety and Tolerability of Different Doses / Formulations of AFFITOPE AD02 in Early Alzheimer's Disease |
Completed |
AFFITOPE AD02 |
Dec. 11, 2013 |
|
| 241 |
NCT00606476 |
AAB-001 (Bapineuzumab) Open-Label, Long-Term Extension Study in Patients With Mild to Moderate Alzheimer's Disease |
Terminated |
Bapineuzumab |
Nov. 25, 2013 |
|
| 242 |
NCT00663026 |
Study Evaluating Bapineuzumab In Alzheimer Disease Subjects |
Completed |
Bapineuzumab |
Nov. 15, 2013 |
|
| 243 |
NCT00663936 |
Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
Edonerpic (T-817MA) |
Nov. 5, 2013 |
|
| 244 |
NCT00153010 |
An Evaluation of Three Doses of NS 2330 in Patients With Mild to Moderate Dementia of the Alzheimer's Type |
Completed |
Tesofensine |
Oct. 29, 2013 |
|
| 245 |
NCT00500500 |
Effect of EGb 761® on Patients With Mild to Moderate Alzheimer's Disease |
Terminated |
Ginkgo biloba |
Oct. 11, 2013 |
|
| 246 |
NCT01354691 |
Safety and Efficacy Study of Ladostigil in Mild to Moderate Probable Alzheimer's Disease |
Completed |
Ladostigil hemitartrate |
July 23, 2013 |
|
| 247 |
NCT00359944 |
Safety and Efficacy Study of AC-3933 in Adults With Mild to Moderate Alzheimer's Disease |
Completed |
AC-3933 |
July 2, 2013 |
|
| 248 |
NCT01023685 |
To Investigate the Safety and Tolerability of Repeated Subcutaneous Injections of CAD106 in Alzheimer's Patients |
Completed |
CAD106 |
June 26, 2013 |
|
| 249 |
NCT01600469 |
NMDA-enhancing Agent for Treatment of Mild Cognitive Impairment and Mild Alzheimer's Disease |
Completed |
DAOI-B |
June 4, 2013 |
|
| 250 |
NCT00930059 |
A Study Of PF-04447943 Compared To Placebo In Subjects With Mild To Moderate Alzheimer's Disease |
Completed |
PF-04447943 |
April 16, 2013 |
|
| 251 |
NCT00620191 |
Metformin in Amnestic Mild Cognitive Impairment |
Completed |
Metformin |
March 14, 2013 |
|
| 252 |
NCT00151398 |
Study Evaluating Lecozotan SR in Mild to Moderate Alzheimer's Disease (AD) |
Completed |
Lecozotan, Donepezil |
Feb. 11, 2013 |
|
| 253 |
NCT01117948 |
Efficacy and Safety of Lornoxicam in Patients With Mild to Moderate Probable Alzheimer's Disease. |
Terminated |
Lornoxicam |
Feb. 6, 2013 |
|
| 254 |
NCT00895895 |
Study Comparing 3 Dosage Levels Of SAM-531 In Outpatients With Mild To Moderate Alzheimer Disease |
Terminated |
Cerlapirdine (SAM-531) |
Jan. 31, 2013 |
|
| 255 |
NCT00948909 |
Efficacy and Safety Study for Subjects With Mild-to-Moderate Alzheimer's Disease |
Completed |
ABT-126, Donepezil |
Jan. 31, 2013 |
|
| 256 |
NCT01137526 |
Efficacy and Safety Study of ABT-384 in Subjects With Mild-to-Moderate Alzheimer's Disease |
Completed |
ABT-384, Donepezil |
Jan. 29, 2013 |
|
| 257 |
NCT00334568 |
Effects Of Rosiglitazone (Extended Release Tablets) On Cerebral Glucose Utilisation And Cognition Alzheimers Disease |
Terminated |
Rosiglitazone |
Jan. 14, 2013 |
|
| 258 |
NCT01547169 |
Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 21 Days |
Completed |
Insulin Detemir |
Dec. 18, 2012 |
|
| 259 |
NCT01350362 |
Efficacy, Safety and Tolerability of Tideglusib to Treat Mild-to-Moderate Alzheimer's Disease Patients |
Completed |
Tideglusib |
Oct. 2, 2012 |
|
| 260 |
NCT01696123 |
Efficacy and Tolerability of MLC601 in Patients With Mild to Moderate Alzheimer Disease Who Were Unable to Tolerate or Failed to Benefit From Treatment With Rivastigmine |
Completed |
MLC601 |
Sept. 28, 2012 |
|
| 261 |
NCT01148498 |
A Biomarker Study of Solanezumab in Patients With and Without Alzheimer's |
Completed |
Solanezumab |
Sept. 25, 2012 |
|
| 262 |
NCT00438568 |
SNIFF 120: Study of Nasal Insulin to Fight Forgetfulness (120 Days) |
Completed |
Insulin |
Sept. 14, 2012 |
|
| 263 |
NCT00083421 |
Effects of ONO-2506PO in Patients With Alzheimer's Disease |
Completed |
Arundic acid (ONO-2506PO) |
June 13, 2012 |
|
| 264 |
NCT00087724 |
A Randomized Study to Evaluate FK962 in Subjects With Mild to Moderate Alzheimer's Disease |
Terminated |
FK962 |
June 7, 2012 |
|
| 265 |
NCT00842673 |
Preliminary Efficacy and Safety Study of ST101 in Alzheimer's Disease |
Completed |
ST-101 |
June 7, 2012 |
|
| 266 |
NCT00842816 |
Preliminary Efficacy and Safety Study of ST101 Plus Aricept in Alzheimer's Disease |
Completed |
ST-101 |
June 7, 2012 |
|
| 267 |
NCT00174525 |
Safety Study of Passive Immunization for Patients With Mild to Moderate Alzheimer's Disease |
Unknown status |
Bapineuzumab (AAB-001) |
May 9, 2012 |
|
| 268 |
NCT00795418 |
Safety and Tolerability of Repeated Subcutaneous Injections of CAD 106 in Mild Alzheimer's Patients |
Completed |
CAD106 |
May 4, 2012 |
|
| 269 |
NCT01569516 |
Study of Octohydroaminoacridine Succinate Tablets in Patients With Alzheimer's Disease |
Unknown status |
Octohydroaminoacridine succinate |
April 9, 2012 |
|
| 270 |
NCT00112073 |
AAB-001 in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
Bapineuzumab |
March 14, 2012 |
|
| 271 |
NCT01019421 |
Lu AE58054 Added to Donepezil for the Treatment for Moderate Alzheimer's Disease |
Completed |
Idalopirdine (Lu AE58054) |
Jan. 6, 2012 |
|
| 272 |
NCT00744978 |
Evaluation of the Efficacy of Varenicline on Cognition, Safety, Tolerability and Pharmacokinetics in Subjects With Mild-to-Moderate Alzheimer's Disease |
Completed |
Varenicline |
Nov. 22, 2011 |
|
| 273 |
NCT00809510 |
A Study of the Long-term Safety of ABT-089 for Subjects With Mild-to-moderate Alzheimer's Disease Who Participated in the M06-876 Study |
Terminated |
Pozanicline (ABT-089) |
Sept. 2, 2011 |
|
| 274 |
NCT00555204 |
Safety and Efficacy Study of ABT-089 in Adults With Mild to Moderate Alzheimer's Disease |
Terminated |
Pozanicline (ABT-089) |
Aug. 23, 2011 |
|
| 275 |
NCT00242593 |
Rosiglitazone Effects on Cognition for Adults in Later Life |
Unknown status |
Rosiglitazone |
Aug. 5, 2011 |
|
| 276 |
NCT01120002 |
Efficacy and Safety of Tamibarotene (OAM80) for Alzheimer's Disease |
Unknown status |
Tamibarotene |
July 22, 2011 |
|
| 277 |
NCT01125683 |
To Evaluate Effects of AZD1446, Placebo and Donepezil in Patients With Alzheimer's Disease |
Terminated |
AZD1446 |
May 13, 2011 |
|
| 278 |
NCT01039701 |
4 Week, Safety and Tolerability Study in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
AZD1446 |
Aug. 11, 2010 |
|
| 279 |
NCT01066481 |
A Study Of Oral PF-01913539 In Patients With Mild To Moderate Alzheimer's Disease |
Withdrawn |
Latrepirdine (PF-01913539) |
June 29, 2010 |
|
| 280 |
NCT00749216 |
Solanezumab Safety Study in Japanese Patients With Alzheimer's Disease |
Completed |
Solanezumab |
June 2, 2010 |
|
| 281 |
NCT00165659 |
A Multi-Center, Randomized, Double-Blind, Parallel Group Study With 3 Groups Receiving Placebo, 5 mg of E2020 and 10 mg of E2020 |
Completed |
Donepezil |
Jan. 29, 2010 |
|
| 282 |
NCT01055392 |
Disease-modifying Properties of Lithium in the Neurobiology of Alzheimer's Disease |
Unknown status |
Lithium cation |
Jan. 25, 2010 |
|
| 283 |
NCT00224497 |
A Dose Ranging Study To Investigate The Efficacy And Safety Of SB-742457 In Alzheimer's Disease |
Completed |
Intepirdine (SB-742457) |
Dec. 24, 2009 |
|
| 284 |
NCT00063310 |
ALADDIN Study: Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation |
Completed |
Leuprolide |
Dec. 11, 2009 |
|
| 285 |
NCT00076440 |
Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation (ALADDIN) VP 104 Study |
Completed |
Leuprolide |
Dec. 11, 2009 |
|
| 286 |
NCT00093951 |
SGS742 in Patients With Mild to Moderate Alzheimer's Disease (AD) |
Completed |
SGS-742 |
Dec. 11, 2009 |
|
| 287 |
NCT00105105 |
Mifepristone as Adjunctive Therapy in Alzheimer's Disease |
Terminated |
Mifepristone |
Dec. 11, 2009 |
|
| 288 |
NCT00443417 |
A Trial of SK-PC-B70M in Mild to Moderate Alzheimer's Disease |
Completed |
SK-PC-B70M |
Dec. 9, 2009 |
|
| 289 |
NCT00099710 |
Curcumin in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
Curcumin |
Dec. 3, 2009 |
|
| 290 |
NCT01001637 |
Efficacy and Safety of Curcumin Formulation in Alzheimer's Disease |
Unknown status |
Curcumin |
Oct. 26, 2009 |
|
| 291 |
NCT00329082 |
Effects of LY2062430 in Subjects With Mild-to-Moderate Alzheimer's Disease and in Healthy Volunteers |
Completed |
Solanezumab (LY2062430) |
Oct. 7, 2009 |
|
| 292 |
NCT00481520 |
Study Evaluating the Safety,Tolerability, PK and PD of SAM-531 in the Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
Cerlapirdine (SAM-531) |
Sept. 30, 2009 |
|
| 293 |
NCT00021723 |
Randomized Safety, Tolerability and Pilot Efficacy of AN-1792 in Alzheimer's Disease |
Terminated |
AN-1792 (AIP-001) |
Sept. 24, 2009 |
|
| 294 |
NCT00982202 |
Pioglitazone in Alzheimer Disease |
Completed |
Pioglitazone |
Sept. 23, 2009 |
|
| 295 |
NCT00880412 |
A Study to Determine the Clinical Safety/Tolerability and Exploratory Efficacy of EHT 0202 as Adjunctive Therapy to Acetylcholinesterase Inhibitor in Mild to Moderate Alzheimer's Disease |
Completed |
EHT 0202 |
Sept. 21, 2009 |
|
| 296 |
NCT00151333 |
Study Evaluating SRA-333 in Mild to Moderate Alzheimer's Disease (AD) |
Completed |
Lecozotan (SRA-333) |
Sept. 4, 2009 |
|
| 297 |
NCT00130429 |
Safety and Effect on Memory of PYM50028 in Mild Alzheimer's Disease |
Completed |
Smilagenin (PYM50028) |
Aug. 21, 2009 |
|
| 298 |
NCT00141661 |
A Safety and Tolerability Evaluation of Two 10-Week Dose Regimens of Orally-Administered PF-04494700 in Alzheimer's Patients |
Completed |
Azeliragon (PF-04494700) |
Aug. 20, 2009 |
|
| 299 |
NCT00672945 |
A Study of PRX-03140 in Subjects With Alzheimer's Disease Receiving a Stable Dose of Donepezil |
Terminated |
PRX-03140 |
July 30, 2009 |
|
| 300 |
NCT00693004 |
Study of PRX-03140 Monotherapy in Subjects With Alzheimer's Disease |
Terminated |
PRX-03140 |
July 30, 2009 |
|
| 301 |
NCT00602680 |
Effect on Cognitive Performance and Safety/Tolerability of SSR180711C in Mild Alzheimer's Disease |
Terminated |
SSR180711C, Donepezil |
July 20, 2009 |
|
| 302 |
NCT00104273 |
Rasagiline 1 mg and 2 mg Added to Aricept 10 mg Daily in Patients With Mild to Moderate Alzheimer's Disease (AD) |
Completed |
Rasagiline |
July 15, 2009 |
|
| 303 |
NCT00927108 |
Rajavtihi Neuronal Adult Stem Cells Project |
Unknown status |
Progenitor Stem Cell Culture |
June 24, 2009 |
|
| 304 |
NCT00911807 |
Comparative Study to Test Safety and Efficacy of Neurotrophic and Cholinergic Treatment of Alzheimer's Disease |
Completed |
Donepezil, Cerebrolysin |
June 10, 2009 |
|
| 305 |
NCT00348192 |
SB-742457 And Donepezil In Alzheimer's Disease |
Completed |
Intepirdine (SB-742457), Donepezil |
June 2, 2009 |
|
| 306 |
NCT00018343 |
Alzheimer's Disease and Aging: Therapeutic Potential of Estrogen |
Completed |
Estradiol |
Jan. 21, 2009 |
|
| 307 |
NCT00018382 |
Insulin, Neurogenetics and Memory in Alzheimer's Disease |
Completed |
Rosiglitazone |
Jan. 21, 2009 |
|
| 308 |
NCT00006399 |
Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease |
Completed |
Donepezil, Estradiol, Progesterone |
Jan. 15, 2009 |
|
| 309 |
NCT00142805 |
Ketasyn in Mild to Moderate Alzheimer's Disease |
Completed |
Tricaprylin (AC-1202) |
Dec. 31, 2008 |
|
| 310 |
NCT00285077 |
Long-Term Safety Extension With SR57667B in Patients With Alzheimer's Disease |
Completed |
Paliroden (SR57667B) |
Dec. 23, 2008 |
|
| 311 |
NCT00357357 |
European Study of HF0220 in Mild to Moderate Alzheimer's Disease Patients |
Completed |
7-beta-Hydroxyepiandrosterone |
Aug. 21, 2008 |
|
| 312 |
NCT00257673 |
Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
MEM 1003 |
May 6, 2008 |
|
| 313 |
NCT00454870 |
Safety and Efficacy of MEM 3454 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease |
Completed |
Facinicline |
May 6, 2008 |
|
| 314 |
NCT00001662 |
Treatment of Alzheimer's Disease With CX516 (Ampalex) |
Completed |
CX516 |
March 4, 2008 |
|
| 315 |
NCT00001933 |
Nefiracetam in the Treatment of Alzheimer's Disease |
Completed |
Nefiracetam |
March 4, 2008 |
|
| 316 |
NCT00088387 |
Effect of Lithium and Divalproex in Alzheimer's Disease |
Completed |
Valproic Acid, Lithium cation |
March 4, 2008 |
|
| 317 |
NCT00083590 |
Huperzine A in Alzheimer's Disease |
Completed |
Huperzine A |
Feb. 21, 2008 |
|
| 318 |
NCT00515333 |
TRx0014 in Patients With Mild or Moderate Alzheimer's Disease |
Completed |
Methylene blue |
Feb. 20, 2008 |
|
| 319 |
NCT00608946 |
Treatment With Copper in Patients With Mild Alzheimer's Dementia |
Completed |
Copper |
Feb. 6, 2008 |
|
| 320 |
NCT00606164 |
Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics Study of Bryostatin 1 in Patients With Alzheimer's Disease |
Unknown status |
Bryostatin 1 |
Feb. 1, 2008 |
|
| 321 |
NCT00384423 |
Short Term Effects of PRX-03140 in Patients With Mild Alzheimer's Disease Being Treated With Aricept |
Completed |
PRX-03140 |
Jan. 30, 2008 |
|
| 322 |
NCT00471211 |
Study Evaluating the Safety, Tolerability and Efficacy of PBT2 in Patients With Early Alzheimer's Disease |
Completed |
PBT2 |
Jan. 16, 2008 |
|
| 323 |
NCT00244322 |
Effects of LY450139 Dihydrate on Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
Semagacestat (LY450139) |
May 28, 2007 |
|
| 324 |
NCT00414622 |
GTS21-201 for Alzheimer Disease:GTS-21 Administered Daily for 28 Days to Participants With Probable Alzheimer's Disease |
Completed |
GTS-21 (DMXB-A) |
April 19, 2007 |
|
| 325 |
NCT00024531 |
Lipitor as a Treatment for Alzheimer's Disease |
Completed |
Atorvastatin |
Nov. 9, 2006 |
|
| 326 |
NCT00069849 |
A Study of the Safety and Efficacy of Multiple Doses of ABT-089 in Subjects With Alzheimer's Disease |
Terminated |
Pozanicline (ABT-089) |
Sept. 4, 2006 |
|
| 327 |
NCT00051909 |
Efficacy and Safety of LY451395 in Patients With Probable Alzheimer's Disease |
Completed |
Mibampator (LY451395) |
July 19, 2006 |
|
| 328 |
NCT00285025 |
Study of the Effect of SR57667B in Patients With Alzheimer's Disease |
Completed |
Paliroden (SR57667B) |
Feb. 1, 2006 |
|
| 329 |
NCT00154635 |
Efficacy and Safety Study of DCB-AD1 in Patients With Mild to Moderate Alzheimer's Disease |
Unknown status |
DCB-AD1 |
Sept. 12, 2005 |
|
| # |
ID |
Title |
Status |
Agent |
Date updated |
Details |
| 1 |
NCT03635047 |
A Phase I Study for Safety and Tolerability of AL002. |
Active, not recruiting |
AL002 |
July 9, 2020 |
|
| 2 |
NCT03971123 |
Study to Compare the Pharmacokinetics of Tricaprilin Formulations and a Placebo on Ketone Body Production |
Completed |
Tricaprylin |
July 8, 2020 |
|
| 3 |
NCT04268953 |
Study to Compare the Pharmacokinetics of Daily Administration of Tricaprilin on Ketone Body Production |
Completed |
Tricaprylin |
July 8, 2020 |
|
| 4 |
NCT04308304 |
MK-1942/Donepezil Interactions in Participants With Alzheimer's Disease (MK-1942-005) |
Not yet recruiting |
Donepezil, MK-1942 |
July 8, 2020 |
|
| 5 |
NCT04023994 |
A Single Ascending Dose Study to Investigate the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Intravenously Administered RO7126209 in Healthy Participants |
Active, not recruiting |
RO7126209 |
June 30, 2020 |
|
| 6 |
NCT04208152 |
A First-in-Human Study of Single and Multiple Doses of anle138b in Healthy Subjects |
Recruiting |
anle138b |
June 23, 2020 |
|
| 7 |
NCT02502253 |
BDPP Treatment for Mild Cognitive Impairment (MCI) and Prediabetes or Type 2 Diabetes Mellitus (T2DM) |
Recruiting |
Resveratrol |
June 17, 2020 |
|
| 8 |
NCT02614131 |
A Study of LY2599666 in Healthy Participants and Participants With Mild Cognitive Impairment or Alzheimer's Disease (AD) |
Terminated |
LY2599666, Solanezumab |
June 17, 2020 |
|
| 9 |
NCT02624778 |
A Study of LY3002813 in Participants With Memory Damage Due to Alzheimer's Disease (AD) or AD |
Completed |
LY3002813 |
June 12, 2020 |
|
| 10 |
NCT03274817 |
A Proof of Concept Study of the Prevention of Mild Cognitive Impairment and Eventual Alzheimer's Disease Using F18 Flutemetamol |
Terminated |
Escitalopram, Venlafaxine |
June 2, 2020 |
|
| 11 |
NCT04040348 |
Alzheimer's Disease Stem Cells Multiple Infusions |
Recruiting |
hUCB-MSCs |
May 28, 2020 |
|
| 12 |
NCT03852901 |
Sodium-glucose Co Transporter 2 (sGLT2) Inhibitor and Endogenous Ketone Production |
Recruiting |
Empagliflozin |
May 21, 2020 |
|
| 13 |
NCT02462161 |
Study of Nasal Insulin to Fight Forgetfulness - Short-Acting Insulin Aspart |
Completed |
Insulin Aspart |
May 12, 2020 |
|
| 14 |
NCT04074837 |
Phase1a, Dose-escalation Study of NNI-362 in Healthy Aged Volunteers |
Recruiting |
NNI-362 |
May 6, 2020 |
|
| 15 |
NCT01747213 |
Bisnorcymserine in Healthy Adult Volunteers |
Completed |
BNC |
April 16, 2020 |
|
| 16 |
NCT01966666 |
A Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy Study of TPI-287 in Alzheimer's Disease |
Completed |
TPI-287 |
April 14, 2020 |
|
| 17 |
NCT03277573 |
Salsalate in Patients Mild to Moderate Alzheimer's Disease |
Active, not recruiting |
Salsalate |
April 14, 2020 |
|
| 18 |
NCT02695004 |
Safety, Tolerability and Pharmacokinetics of DKF-310 ( (Donepezil). |
Completed |
Donepezil (DKF-310) |
April 6, 2020 |
|
| 19 |
NCT03998423 |
Oral Fecal Microbiota Transplant Feasibility Study in Alzheimer's Disease |
Suspended |
Fecal Microbiota Transplant |
March 27, 2020 |
|
| 20 |
NCT03056729 |
Single-Ascending-Dose Study of BIIB076 in Healthy Volunteers and Participants With Alzheimer's Disease |
Completed |
BIIB076 |
March 24, 2020 |
|
| 21 |
NCT04121208 |
MIcroglial Colony Stimulating Factor-1 Receptor (CSF1R) in Alzheimer's Disease |
Not yet recruiting |
JNJ-40346527 |
March 24, 2020 |
|
| 22 |
NCT03757325 |
Study to Evaluate DNL747 in Subjects With Alzheimer's Disease |
Completed |
DNL747 |
Feb. 26, 2020 |
|
| 23 |
NCT03819699 |
Study With Lu AF20513 in Patients With Mild Alzheimer's Disease (AD) or Mild Cognitive Impairment (MCI) Due to AD |
Terminated |
Lu AF20513 |
Feb. 21, 2020 |
|
| 24 |
NCT03522129 |
Study to Evaluate the Effect of CT1812 Treatment on Amyloid Beta Oligomer Displacement Into CSF in Subjects With Mild to Moderate Alzheimer's Disease |
Recruiting |
CT1812 |
Feb. 5, 2020 |
|
| 25 |
NCT03748303 |
Allopregnanolone Regenerative Therapeutic for Early Alzheimer's Disease: Intramuscular Study |
Recruiting |
Brexanolone |
Jan. 29, 2020 |
|
| 26 |
NCT03706885 |
Efavirenz for Patients With Alzheimer's Disease |
Recruiting |
Efavirenz |
Jan. 27, 2020 |
|
| 27 |
NCT03698695 |
A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male Volunteers |
Completed |
Donepezil, Mefloquine |
Jan. 22, 2020 |
|
| 28 |
NCT03943264 |
A Biomarker-directed Study of XPro1595 in Patients With Mild to Moderate Alzheimer's |
Recruiting |
XPro1595 |
Jan. 22, 2020 |
|
| 29 |
NCT03375697 |
A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-63733657 in Healthy Subjects and Subjects With Alzheimer's Disease |
Completed |
JNJ-63733657 |
Jan. 13, 2020 |
|
| 30 |
NCT03935568 |
A Single and Multiple Ascending Dose Study to Evaluate the Safety and Pharmacokinetics of PU-AD in Healthy Subjects |
Completed |
PU-AD |
Dec. 26, 2019 |
|
| 31 |
NCT02388152 |
Study to Evaluate the Safety and Tolerability of a New Drug Named Lu AF20513 in Patients With Mild Alzheimer's Disease |
Terminated |
Lu AF20513 |
Nov. 29, 2019 |
|
| 32 |
NCT03668405 |
A Study to Evaluate the Long-term Safety and Tolerability of Lu AF20513 and the Antibody Response in Patients With Alzheimer's Disease (AD) |
Terminated |
Lu AF20513 |
Nov. 21, 2019 |
|
| 33 |
NCT03634007 |
Gene Therapy for APOE4 Homozygote of Alzheimer's Disease |
Recruiting |
AAVrh.10hPOE2 |
Nov. 20, 2019 |
|
| 34 |
NCT04157712 |
Multiple Ascending Dose Study of ALZ-801 |
Completed |
ALZ-801 |
Nov. 19, 2019 |
|
| 35 |
NCT01677572 |
Multiple Dose Study of Aducanumab (BIIB037) (Recombinant, Fully Human Anti-Aβ IgG1 mAb) in Participants With Prodromal or Mild Alzheimer's Disease |
Terminated |
Aducanumab |
Nov. 12, 2019 |
|
| 36 |
NCT02600130 |
Allogeneic Human Mesenchymal Stem Cell Infusion Versus Placebo in Patients With Alzheimer's Disease |
Active, not recruiting |
Longeveron Mesenchymal Stem Cells |
Nov. 6, 2019 |
|
| 37 |
NCT04149860 |
Study With Lu AF87908 in Healthy Subjects and Patients With Alzheimer's Disease |
Recruiting |
Lu AF87908 |
Nov. 4, 2019 |
|
| 38 |
NCT04133454 |
Evaluation of Safety and Tolerability of Libella Gene Therapy for Alzheimer's Disease: AAV- hTERT |
Recruiting |
AAV-hTERT |
Oct. 28, 2019 |
|
| 39 |
NCT03802162 |
A Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-355 |
Completed |
CKD-355 |
Oct. 23, 2019 |
|
| 40 |
NCT01133405 |
A Safety Study of LY2886721 Single Doses in Healthy Subjects |
Completed |
LY-2886721 |
Sept. 16, 2019 |
|
| 41 |
NCT03298672 |
Safety, Tolerability, and Pharmacokinetics Study of NDX-1017 |
Completed |
NDX-1017 |
Sept. 10, 2019 |
|
| 42 |
NCT03008161 |
Multiple Dose Safety Study of NPT088 in Patients With Mild to Moderate Probable Alzheimer's Disease |
Completed |
NPT088 |
Aug. 15, 2019 |
|
| 43 |
NCT03056495 |
Clinical Trial to Determine Tolerable Dosis of Vorinostat in Patients With Mild Alzheimer Disease |
Recruiting |
Vorinostat |
Aug. 1, 2019 |
|
| 44 |
NCT02353598 |
A Study of Crenezumab in Participants With Mild to Moderate Alzheimer Disease |
Completed |
Crenezumab |
July 24, 2019 |
|
| 45 |
NCT01227252 |
A Safety Study of LY2886721 Multiple Doses in Healthy Subjects |
Completed |
LY-2886721 |
July 19, 2019 |
|
| 46 |
NCT01807026 |
A Study of LY2886721 in Healthy Participants and Participants Diagnosed With Alzheimer's Disease |
Completed |
LY-2886721 |
July 19, 2019 |
|
| 47 |
NCT02221622 |
Allopregnanolone for Mild Cognitive Impairment Due to Alzheimer's Disease or Mild AD |
Completed |
Brexanolone |
July 5, 2019 |
|
| 48 |
NCT03019536 |
A Study of LY3303560 in Participants With Mild Cognitive Impairment or Alzheimer's Disease |
Completed |
LY3303560 |
July 5, 2019 |
|
| 49 |
NCT02288000 |
Prediction of Cognitive Properties of Memantine for Neurodegenerative Diseases |
Recruiting |
Memantine |
June 27, 2019 |
|
| 50 |
NCT02769065 |
Study of TAK-071 in Healthy Participants and Participants With Mild Cognitive Impairment/Mild Alzheimer Disease and Relative Bioavailability (BA) and Food Effect of TAK-071 in Healthy Participants |
Terminated |
Donepezil, TAK-071 |
June 10, 2019 |
|
| 51 |
NCT03720548 |
A Study of LY3372993 in Healthy Participants and Participants With Alzheimer's Disease (AD) |
Completed |
LY3372993 |
June 5, 2019 |
|
| 52 |
NCT02036645 |
SAD/MAD Study to Assess Safety, Tolerability, PK & PD of MEDI1814 in Subjects With Mild-Moderate Alzheimer's Disease. |
Completed |
MEDI1814 |
June 3, 2019 |
|
| 53 |
NCT02471833 |
Health Evaluation in African Americans Using RAS Therapy |
Recruiting |
Telmisartan |
June 3, 2019 |
|
| 54 |
NCT03551769 |
Pharmacokinetics of Tricaprilin Including Food Effect on Ketone Body Production |
Completed |
Tricaprylin |
May 29, 2019 |
|
| 55 |
NCT03955380 |
MAD Phase I Study to Investigate Contraloid Acetate |
Completed |
Contraloid |
May 20, 2019 |
|
| 56 |
NCT03944460 |
SAD Phase I Study (First-in-human) to Investigate Contraloid Acetate |
Completed |
Contraloid |
May 9, 2019 |
|
| 57 |
NCT03740178 |
Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005) |
Not yet recruiting |
MK-4334, Donepezil |
May 3, 2019 |
|
| 58 |
NCT03822208 |
First in Human Study for Safety and Tolerability of AL003. |
Recruiting |
AL003 |
April 19, 2019 |
|
| 59 |
NCT03838185 |
Study to Assess the Safety, Tolerability and Pharmacokinetics of Single Ascending Oral Doses of J147 |
Recruiting |
J147 |
Feb. 12, 2019 |
|
| 60 |
NCT02360657 |
Study Investigating the Effects of JNJ-54861911 on Amyloid-beta Processing in Cerebrospinal Fluid (CSF) and Plasma in Japanese Participants Asymptomatic at Risk for Alzheimer Dementia |
Completed |
Atabecestat (JNJ-54861911) |
Feb. 4, 2019 |
|
| 61 |
NCT01406145 |
A Study of the Safety and Tolerability of ASP0777 in Subjects With Alzheimer's Disease (AD) Taking a Stable Dose of Donepezil |
Completed |
ASP0777 |
Jan. 30, 2019 |
|
| 62 |
NCT03752294 |
A Novel Therapeutic Target for Alzheimer's Disease in Men and Women 50-85 Years of Age. |
Not yet recruiting |
Dabigatran |
Nov. 23, 2018 |
|
| 63 |
NCT03418688 |
A Multiple Ascending Dose Study of COR388 |
Completed |
COR388 |
Nov. 7, 2018 |
|
| 64 |
NCT03316898 |
A FDG-PET Study of AGN-242071 Added to Standard-of-Care (Donepezil ± Memantine) for the Treatment of Participants With Mild to Moderate Alzheimer's Disease |
Withdrawn |
Donepezil, AGN-242071, Memantine |
Nov. 2, 2018 |
|
| 65 |
NCT02509117 |
First-In-Human Study Of Single And Multiple Ascending Doses Of PF-06751979 |
Completed |
PF-06751979 |
Nov. 1, 2018 |
|
| 66 |
NCT03179501 |
NP001, Alzheimer's Disease, and Blood Markers of Inflammation |
Terminated |
NP001 |
Oct. 22, 2018 |
|
| 67 |
NCT00874939 |
A Study to Evaluate the Effects of MK-0249 and an Alzheimer's Disease Medication on Cognitive Function in Adults With Alzheimer's Disease (MK-0249-023) |
Terminated |
MK-0249, Donepezil |
Oct. 17, 2018 |
|
| 68 |
NCT00827034 |
A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects |
Completed |
Latrepirdine, Warfarin |
Oct. 16, 2018 |
|
| 69 |
NCT03030105 |
Study to Evaluate the Effects of BPN14770 on Scopolamine-induced Cognitive Impairment in Healthy Volunteers |
Completed |
Donepezil, BPN14770, Scopolamine |
Oct. 16, 2018 |
|
| 70 |
NCT02593318 |
Trial of Oxaloacetate in Alzheimer's Disease (TOAD) |
Completed |
Oxaloacetate |
Oct. 12, 2018 |
|
| 71 |
NCT02910739 |
An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016) |
Completed |
Verubecestat (MK-8931) |
Oct. 1, 2018 |
|
| 72 |
NCT02793232 |
Clinical Trial In Healthy Volunteers And Health Elderly Volunteers To Evaluate The Safety, Tolerability And Blood Concentration After Single And Multiple Escalating Oral Doses Of PF-06751979. |
Completed |
PF-06751979 |
Sept. 17, 2018 |
|
| 73 |
NCT03438604 |
A Study to Evaluate the Effect of Heat Application on the Delivery Profile of Corplex™ Donepezil Transdermal Delivery System (TDS) |
Completed |
Donepezil |
Sept. 14, 2018 |
|
| 74 |
NCT03432195 |
A Clinical Study to Evaluate the Pharmacokinetics (PK) of Corplex™ Donepezil Transdermal Delivery System (TDS) Applied to Different Body Locations |
Completed |
Donepezil |
Aug. 7, 2018 |
|
| 75 |
NCT02968719 |
A Phase 1, Corplex™ Donepezil Transdermal System Compared to Oral Aricept® |
Completed |
Donepezil |
Aug. 1, 2018 |
|
| 76 |
NCT03259958 |
A Bioequivalence Study of Corplex™ Donepezil Transdermal Delivery System Compared to Aricept® |
Completed |
Donepezil |
Aug. 1, 2018 |
|
| 77 |
NCT02754830 |
A Study of LY3303560 in Healthy Participants and Participants With Alzheimer's Disease (AD) |
Completed |
LY3303560 |
July 23, 2018 |
|
| 78 |
NCT03456349 |
Multi-centre Study of HTL0018318 in Patients as an add-on to Standard-of-care |
Completed |
HTL0018318 |
July 20, 2018 |
|
| 79 |
NCT03307993 |
Positron Emission Tomography (PET) Study in Patients With Alzheimer's Disease |
Terminated |
Idalopirdine |
April 4, 2018 |
|
| 80 |
NCT03093519 |
A Repeated Dose Study of KHK6640 in Japanese Patients With Alzheimer's Disease |
Completed |
KHK6640 |
March 20, 2018 |
|
| 81 |
NCT00408525 |
Donepezil and Brain Activity Patterns in Those at Risk For Alzheimer's Disease |
Completed |
Donepezil |
Feb. 5, 2018 |
|
| 82 |
NCT01837641 |
A Study of LY3002813 in Participants With Alzheimer's Disease |
Completed |
LY3002813 |
Dec. 26, 2017 |
|
| 83 |
NCT02392468 |
Study of Systemic and Ocular Safety and Pharmacokinetics of BI 409306 in Patients With Schizophrenia, Alzheimer's Disease, and Healthy Volunteers |
Completed |
BI 409306 |
Dec. 20, 2017 |
|
| 84 |
NCT01702467 |
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single, Oral Escalating Doses of GSK2647544 in Healthy Volunteers |
Completed |
GSK2647544 |
Oct. 18, 2017 |
|
| 85 |
NCT00468897 |
A Study To Demonstrate The Bioequivalence Of Rosiglitazone XR (BRL-049653) 8mgs XR Manufactured At Two Different Sites. |
Completed |
Rosiglitazone |
Aug. 7, 2017 |
|
| 86 |
NCT00459550 |
A Clinical Study to Assess Single and Repeat Doses of a New Medication (GSK933776) in Patients With Alzheimer's Disease |
Completed |
GSK933776 |
July 21, 2017 |
|
| 87 |
NCT00733785 |
PK, Dose Proportionality, Food Effect And Repeat Dose Study Of Rosiglitazone XR In Healthy Volunteers |
Completed |
Rosiglitazone |
July 21, 2017 |
|
| 88 |
NCT02820896 |
A Study of RO7105705 in Healthy Participants and Participants With Mild-to-Moderate Alzheimer's Disease |
Completed |
Semorinemab |
July 21, 2017 |
|
| 89 |
NCT00675090 |
Bridging Study With GSK239512 In Patients With Mild To Moderate Alzheimer's Disease |
Completed |
GSK-239512 |
July 7, 2017 |
|
| 90 |
NCT00013650 |
Effects of an Anti-Inflammatory Drug in Alzheimer's Disease |
Completed |
Cyclophosphamide |
July 2, 2017 |
|
| 91 |
NCT00937846 |
Brain Uptake of GSK1034702: a Positron Emission Tomography (PET) Scan Study |
Completed |
GSK1034702 |
June 27, 2017 |
|
| 92 |
NCT02291783 |
Phase I, Healthy Subject, Safety, Tolerability and Pharmacokinetic Study of an M1 Agonist to Treat Cognitive Impairment |
Completed |
HTL0009936 |
June 20, 2017 |
|
| 93 |
NCT01424436 |
Modulation of Abeta Levels by GSK933776 in Alzheimer's Disease Patient |
Completed |
GSK933776 |
June 14, 2017 |
|
| 94 |
NCT01978327 |
GSK2647544 RD, DDI in Healthy Young and Elderly Volunteers |
Terminated |
GSK2647544 |
June 8, 2017 |
|
| 95 |
NCT02859207 |
A Study to Evaluate the Pharmacokinetics of E2609 and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared With Healthy Subjects |
Completed |
Elenbecestat |
June 8, 2017 |
|
| 96 |
NCT02127476 |
A Study of Single and Multiple Doses of KHK6640 in Subjects With Prodromal or Mild to Moderate Alzheimer's Disease |
Completed |
KHK6640 |
June 1, 2017 |
|
| 97 |
NCT01702480 |
Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects |
Completed |
GSK2981710 |
May 9, 2017 |
|
| 98 |
NCT03113812 |
Repeated Subcutaneous Administration of ABvac40 in Mild to Moderate Alzheimer's Disease Patients |
Completed |
ABvac40 |
April 14, 2017 |
|
| 99 |
NCT02434718 |
Single and Multiple Ascending Dose Study of Aducanumab (BIIB037) in Japanese Participants With Alzheimer's Disease |
Completed |
Aducanumab |
April 10, 2017 |
|
| 100 |
NCT02537938 |
Neurogenetic Pharmaceuticals (NGP) 555 in Healthy Volunteers (14 Day Multiple Ascending Dose) |
Completed |
NGP 555 |
March 29, 2017 |
|
| 101 |
NCT02031198 |
18-months Safety Follow-up Study of AADvac1, an Active Tau Vaccine for Alzheimer's Disease |
Completed |
AADvac1 |
March 17, 2017 |
|
| 102 |
NCT01369225 |
Open Label Extension Study Evaluating Safety and Tolerability of AAB-003 (PF-05236812) in Subject With Mild to Moderate Alzheimer's Disease |
Completed |
AAB-003 (PF-05236812) |
March 10, 2017 |
|
| 103 |
NCT01193608 |
Study Evaluating The Safety Of AAB-003 (PF-05236812) In Subjects With Alzheimer's Disease |
Completed |
AAB-003 (PF-05236812) |
Feb. 23, 2017 |
|
| 104 |
NCT02546310 |
Phase 1 Study Investigating Effects of HTL0009936 on Cognition and BOLD fMRI Signals in Healthy Elderly Subjects |
Completed |
HTL0009936 |
Feb. 3, 2017 |
|
| 105 |
NCT02051335 |
Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy Adults |
Completed |
Roflumilast, Donepezil |
Feb. 1, 2017 |
|
| 106 |
NCT02648672 |
BPN14770 Single Ascending Dose Study in Healthy Male and Female Subjects |
Completed |
BPN14770 |
Jan. 18, 2017 |
|
| 107 |
NCT02840279 |
A Multiple Ascending Dose Study of BPN14770 in Healthy Young and Elderly Male or Female Subjects |
Completed |
BPN14770 |
Jan. 18, 2017 |
|
| 108 |
NCT02782975 |
Absolute Bioavailability of a Single, Fixed Subcutaneous Dose of Aducanumab in Healthy Participants |
Completed |
Aducanumab |
Jan. 13, 2017 |
|
| 109 |
NCT01600859 |
Evaluation of E2609 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (Study: E2609-A001-101 Amendment 02) |
Completed |
Elenbecestat (E2609) |
Dec. 30, 2016 |
|
| 110 |
NCT02130661 |
Study to Determine the Effect of Itraconazole on the Pharmacokinetics of Rilapladib (SB659032) in Healthy Volunteers |
Withdrawn |
Rilapladib, Itraconazole |
Dec. 13, 2016 |
|
| 111 |
NCT02377713 |
A Single Dose Study of KHK6640 in Japanese Patients With Alzheimer's Disease. |
Completed |
KHK6640 |
Dec. 7, 2016 |
|
| 112 |
NCT01780519 |
The Cognitive Effects of Lorazepam in Healthy Older Individuals With TOMM40 Variable-length Polymorphisms |
Completed |
Lorazepam |
Nov. 10, 2016 |
|
| 113 |
NCT00688207 |
Mild Alzheimer''s Disease to Assess the of Extended Release Formulation of Rosiglitazone (RSG XR) |
Completed |
Rosiglitazone |
Nov. 7, 2016 |
|
| 114 |
NCT00531804 |
A Multiple Ascending Dose Study of R1450 in Patients With Alzheimer Disease. |
Completed |
Gantenerumab |
Nov. 2, 2016 |
|
| 115 |
NCT01701089 |
A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers |
Completed |
L-deprenyl-D2 C-11 |
Nov. 2, 2016 |
|
| 116 |
NCT00087789 |
CERE-110 in Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
CERE-110, Nerve Growth Factor |
Oct. 31, 2016 |
|
| 117 |
NCT02710188 |
Relative Bioavailability Study in Healthy Subjects to Evaluate the Pharmacokinetics of HTL0009936 After One Dose of Prototype Formulation |
Completed |
HTL0009936 |
Oct. 18, 2016 |
|
| 118 |
NCT02142777 |
S-Equol in Alzheimer's Disease (SEAD) Trial |
Completed |
Equol |
Aug. 16, 2016 |
|
| 119 |
NCT02820155 |
Phase I Single and Multiple Escalating Dose Study of RGN1016 in Healthy Male Subjects |
Unknown status |
RGN1016 |
July 6, 2016 |
|
| 120 |
NCT02573740 |
Safety, Tolerability and the Effects on Cerebrospinal Fluid Spectrin Breakdown Product-145 Levels of ABT-957 in Subjects With Mild Alzheimer's Disease and Mild Cognitive Impairment |
Terminated |
ABT-957 |
July 1, 2016 |
|
| 121 |
NCT02220738 |
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ABT-957 in Subjects With Mild-to-Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors |
Terminated |
ABT-957 |
June 16, 2016 |
|
| 122 |
NCT01716637 |
Short Term Efficacy and Safety of Perispinal Administration of Etanercept in Mild to Moderate Alzheimer's Disease |
Completed |
Etanercept |
May 12, 2016 |
|
| 123 |
NCT02323334 |
A Study of LY3202626 in Healthy Participants and Participants With Alzheimer's Disease |
Completed |
LY3202626, Itraconazole |
Feb. 26, 2016 |
|
| 124 |
NCT02386306 |
Study Evaluating Safety, Tolerability, and PK of Multiple Ascending Doses of GC021109 in Subjects With Mild to Moderate Alzheimer's Disease |
Completed |
GC021109 |
Feb. 3, 2016 |
|
| 125 |
NCT02534480 |
Neurogenetic Pharmaceuticals (NGP) 555 in Healthy Young Volunteers (Single-ascending Dose) |
Completed |
NGP 555 |
Jan. 13, 2016 |
|
| 126 |
NCT02211079 |
A Study to Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochrome P450 (CYP) 3A4, CYP2B6, CYP2C9, and CYP1A2 Substrates |
Completed |
Atabecestat (JNJ-54861911), Caffeine, Midazolam, Tolbutamide |
Nov. 24, 2015 |
|
| 127 |
NCT00829816 |
Safety and Tolerability of Dimebon in Patients on Memantine, and Memantine Plus Donepezil |
Completed |
Latrepirdine |
Nov. 10, 2015 |
|
| 128 |
NCT02340195 |
Pharmacokinetic Properties of Idalopirdine (Lu AE58054) in Subjects With and Without Impaired Kidney Function |
Completed |
Idalopirdine |
Nov. 9, 2015 |
|
| 129 |
NCT01496170 |
A Study of the Safety, Tolerability, and Pharmacodynamics of MK-8931 in Participants With Alzheimer's Disease (MK-8931-010 AM1 [P07820 AM1]) |
Completed |
Verubecestat (MK-8931) |
Oct. 23, 2015 |
|
| 130 |
NCT01850238 |
Safety Study of AADvac1, a Tau Peptide-KLH-Conjugate Active Vaccine to Treat Alzheimer's Disease |
Completed |
AADvac1 |
Oct. 12, 2015 |
|
| 131 |
NCT00464334 |
A Study of V950 in People With Alzheimer Disease (V950-001 AM7) |
Completed |
V950, ISCOMATRIX |
Sept. 25, 2015 |
|
| 132 |
NCT02061878 |
A Study to Evaluate the Effect of Bexarotene on Beta-Amyloid and Apolipoprotein E Metabolism in Healthy Subjects |
Completed |
Bexarotene |
Aug. 13, 2015 |
|
| 133 |
NCT01978548 |
A Study to Evaluate the Effects of JNJ-54861911 on Amyloid Beta Processing in Cerebrospinal Fluid and Plasma in Patients With Prodromal Alzheimer's Disease |
Completed |
Atabecestat (JNJ-54861911) |
June 25, 2015 |
|
| 134 |
NCT02094729 |
A Randomized, Double-blind, Placebo-controlled Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamic Response of Repeated Intravenous Infusions of BAN2401 in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease |
Completed |
BAN-2401 |
June 8, 2015 |
|
| 135 |
NCT01072812 |
Study of the Pharmacokinetics and Pharmacodynamics of POSIPHEN® in Subjects With Amnestic Mild Cognitive Impairment |
Terminated |
Posiphen |
April 22, 2015 |
|
| 136 |
NCT00884533 |
QTc Study of Rosi XR in Healthy Volunteers |
Withdrawn |
Rosiglitazone, Moxifloxacin |
April 17, 2015 |
|
| 137 |
NCT01487395 |
Prediction of Cognitive Properties of New Drug Candidates for Neurodegenerative Diseases in Early Clinical Development |
Completed |
Donepezil |
April 9, 2015 |
|
| 138 |
NCT01485302 |
Single and Repeated Dosing Study to Assess the Safety and the Concentration-time Profile of SAR228810 in Alzheimer's Patients |
Completed |
SAR228810 |
March 25, 2015 |
|
| 139 |
NCT02178124 |
A Phase I Clinical Study, Randomized, Single-blind, Placebo-controlled, Multiple Doses, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects. |
Completed |
Donepezil |
March 25, 2015 |
|
| 140 |
NCT01397539 |
Single Ascending Dose Study of BIIB037 in Participants With Alzheimer's Disease |
Completed |
Aducanumab |
March 23, 2015 |
|
| 141 |
NCT01548430 |
A Safety Study of TTP4000 in Subjects With Alzheimer's Disease |
Completed |
TTP4000 |
Feb. 12, 2015 |
|
| 142 |
NCT00954252 |
Safety, Pharmacokinetics and Pharmacodynamics Study of Treatment With CHF 5074 in Healthy Young Male Subjects |
Completed |
CHF 5074 |
Feb. 10, 2015 |
|
| 143 |
NCT01203384 |
Study to Evaluate Safety, Pharmacokinetics and Pharmacodynamics of CHF5074 in Healthy Young Male Subjects |
Completed |
CHF5074 |
Feb. 10, 2015 |
|
| 144 |
NCT01258452 |
Study to Evaluate the Effects of Food Ingestion on the Pharmacokinetics of CHF 5074 in Healthy Young Male Subjects |
Completed |
CHF 5074, CHF 5974 |
Feb. 10, 2015 |
|
| 145 |
NCT01537757 |
A Two-Part, Single-Dose Study of the Pharmacokinetics of MK-8931 in Subjects With Renal Insufficiency (MK-8931-009 [P08535]) |
Completed |
Verubecestat (MK-8931) |
Jan. 26, 2015 |
|
| 146 |
NCT01467726 |
Safety, Pharmacokinetics and Pharmacodynamics of Velusetrag in Healthy Elderly Subjects |
Completed |
Velusetrag |
Dec. 3, 2014 |
|
| 147 |
NCT01827982 |
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of JNJ-54861911 in Healthy Volunteers Compared With Placebo |
Completed |
Atabecestat (JNJ-54861911) |
Nov. 10, 2014 |
|
| 148 |
NCT00110552 |
Effects of Sage on Memory and Mental Performance in Alzheimer's Disease Patients |
Completed |
Sage |
Oct. 29, 2014 |
|
| 149 |
NCT02197884 |
A Study to Assess Effects of Clarithromycin on Pharmacokinetics of JNJ-54861911 in Healthy Male Participants |
Completed |
Atabecestat (JNJ-54861911), Itraconazole, Clarithromycin |
Oct. 15, 2014 |
|
| 150 |
NCT02260700 |
A Study to Evaluate Bioavailability, Food Effect, Safety and Tolerability of a Solid Dosage Formulation of JNJ-54861911 in Healthy Older Male Participants |
Completed |
Atabecestat (JNJ-54861911) |
Oct. 9, 2014 |
|
| 151 |
NCT01656525 |
A Multiple-dose Study of Gantenerumab in Japanese Alzheimer&Apos;s Disease Patients |
Completed |
Gantenerumab |
Sept. 19, 2014 |
|
| 152 |
NCT02180269 |
A Safety, Tolerability and Pharmacokinetics Study of JNJ-54861911 in Healthy Japanese Male Participants |
Completed |
Atabecestat (JNJ-54861911) |
Sept. 12, 2014 |
|
| 153 |
NCT00397891 |
Study Evaluating Single Ascending Doses of AAB-001 Vaccine SAD Japanese Patients With Alzheimers Disease |
Completed |
Bapineuzumab |
Sept. 4, 2014 |
|
| 154 |
NCT00713765 |
Pharmacokinetic Interaction Between AZD3480 and Donepezil |
Terminated |
AZD-0328, Donepezil |
Aug. 15, 2014 |
|
| 155 |
NCT01492374 |
Study to Evaluate the Safety, Tolerability and the Effect of BMS-241027 on Cerebrospinal Fluid Biomarkers in Subjects With Mild Alzheimer's Disease |
Completed |
BMS-241027 |
July 24, 2014 |
|
| 156 |
NCT00750529 |
Alzheimer and Sleep |
Completed |
Galantamine, Donepezil |
July 8, 2014 |
|
| 157 |
NCT02040987 |
AZD3293 Thorough QT Study in Healthy Male Volunteers |
Completed |
Lanabecestat (AZD3293), Moxifloxacin |
July 3, 2014 |
|
| 158 |
NCT01860625 |
A Phase I Clinical, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects |
Completed |
Donepezil |
June 30, 2014 |
|
| 159 |
NCT02126514 |
A Phase I, Open-Label, Single-Center Study to Assess the Absorption, Metabolism, and Excretion of [14C]-AZD3293 |
Completed |
Lanabecestat (AZD3293) |
June 16, 2014 |
|
| 160 |
NCT01864655 |
Safety and Tolerability of AZD0530 (Saracatinib) in Alzheimer's Disease |
Completed |
Saracatinib |
June 13, 2014 |
|
| 161 |
NCT01028911 |
A Study to Evaluate the Safety, Tolerability, and Blood Levels of PF-03654746 in Subjects With Mild to Moderate Alzheimer's Disease |
Terminated |
PF-03654746 |
June 4, 2014 |
|
| 162 |
NCT02005991 |
A Study To Examine The Distribution Of PF-05212377 In The Brain Of Healthy Volunteer Subjects Using Positron Emission Tomography And A Radioactive Tracer Following Oral Administration Of One Dose Of PF-05212377 |
Completed |
PF-05212377 |
April 16, 2014 |
|
| 163 |
NCT01795339 |
A Two-part Multiple Dose Study to Assess the Safety and Effects of AZD3293 in Healthy Elderly and Alzheimer's Patients |
Completed |
Lanabecestat (AZD3293) |
April 3, 2014 |
|
| 164 |
NCT01887535 |
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-54861911 in Healthy Elderly Participants |
Completed |
Atabecestat (JNJ-54861911) |
Jan. 14, 2014 |
|
| 165 |
NCT01908010 |
Safety, Tolerability, and Pharmacokinetics of ABT-354 in Subjects With Mild-to-Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors |
Completed |
ABT-354 |
Dec. 11, 2013 |
|
| 166 |
NCT01254448 |
Multiple Ascending Dose Study of TC-5619 in Healthy Elderly Subjects and Subjects With Alzheimer's Disease |
Completed |
Bradanicline (TC-5619) |
Sept. 4, 2013 |
|
| 167 |
NCT01294540 |
Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2609 in Healthy Subjects and an Elderly Cohort |
Completed |
Elenbecestat (E2609) |
Aug. 29, 2013 |
|
| 168 |
NCT01221259 |
A Randomized, Double-blind, Placebo-controlled, Sequential Ascending, Single-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2212 in Healthy Subjects |
Completed |
E2212 |
May 22, 2013 |
|
| 169 |
NCT01230853 |
A Randomized, Double-blind, Placebo-controlled, Combined Single Ascending Dose and Multiple Ascending Dose Study |
Completed |
BAN-2401 |
May 22, 2013 |
|
| 170 |
NCT01716897 |
An Study to Determine the Bioavailability of E2609 Tablets Compared to Capsules and the Effect of Food on Absorption |
Completed |
Elenbecestat (E2609) |
May 22, 2013 |
|
| 171 |
NCT00975481 |
A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine) In Healthy Recreational Polydrug Users |
Completed |
Latrepirdine, Alprazolam |
April 2, 2013 |
|
| 172 |
NCT00411580 |
Safety and Tolerability Study in Patients With Mild to Moderate Alzheimer's Disease (AD) |
Completed |
CAD106 |
March 29, 2013 |
|
| 173 |
NCT01137799 |
The Effect of JNJ-39393406 on Event Related Potentials in Stable Schizophrenic Patients |
Terminated |
JNJ-39393406 |
Nov. 8, 2012 |
|
| 174 |
NCT01005862 |
Effect of PF-04360365 On ABETA In Patients With Alzheimer's Disease And Healthy Volunteers |
Completed |
Ponezumab (PF-04360365) |
Sept. 26, 2012 |
|
| 175 |
NCT01482013 |
Safety Study of HPP854 in Subjects With Mild Cognitive Impairment or a Diagnosis of Mild Alzheimer's Disease |
Terminated |
HPP854 |
Aug. 30, 2012 |
|
| 176 |
NCT01482845 |
A Phase 1 Study of the Safety, Tolerability and Pharmacokinetics of ABT-126 in Subjects With Alzheimer's Disease |
Completed |
ABT-126 |
May 2, 2012 |
|
| 177 |
NCT01297218 |
The Safety and The Efficacy Evaluation of NEUROSTEM®-AD in Patients With Alzheimer's Disease |
Completed |
Human Umbilical Cord Blood Derived-Mesenchymal Stem Cells |
April 23, 2012 |
|
| 178 |
NCT00766363 |
Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Alzheimer's Disease |
Completed |
Encenicline (EVP-6124), Donepezil, Rivastigmine |
April 20, 2012 |
|
| 179 |
NCT01348737 |
Assessment of Safety, Tolerability and Blood Concentrations of Single Doses of AZD3839 in Healthy Volunteers |
Completed |
AZD-3839 |
April 6, 2012 |
|
| 180 |
NCT01309763 |
Safety and Tolerability of AFFITOPE AD03 |
Completed |
AFFITOPE AD03 |
Dec. 20, 2011 |
|
| 181 |
NCT01454115 |
Study to Evaluate the Safety, Pharmacokinetics and Tolerability of BMS-708163 |
Completed |
Avagacestat (BMS-708163) |
Nov. 21, 2011 |
|
| 182 |
NCT00965588 |
Study to Evaluate Safety, Tolerability and Immunogenicity of Vaccine (UB 311) in Subjects With Alzheimer's Disease |
Completed |
UB 311 |
Aug. 23, 2011 |
|
| 183 |
NCT01125631 |
Multiple Intravenous Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease |
Completed |
Ponezumab (PF-04360365) |
Aug. 12, 2011 |
|
| 184 |
NCT00825084 |
A Phase 1 Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF-01913539] In Japanese And Western Healthy Subjects |
Completed |
Latrepirdine |
April 26, 2011 |
|
| 185 |
NCT00547560 |
Study Evaluating Multiple Doses Of GSI-953 Within The Elderly Population |
Completed |
Begacestat (GSI-953) |
April 4, 2011 |
|
| 186 |
NCT00959881 |
Study Evaluating The Coadministration of Begacestat And Donepezil |
Completed |
Begacestat, Donepezil |
April 4, 2011 |
|
| 187 |
NCT01013610 |
An Escalating Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LNK 754 in Elderly Volunteers and in Subjects With Mild Alzheimer's Disease |
Completed |
CP-609754 |
March 15, 2011 |
|
| 188 |
NCT01297036 |
Pharmacokinetic Comparisons of Two Donepezil Formulations |
Completed |
Donepezil |
Feb. 16, 2011 |
|
| 189 |
NCT01079819 |
Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BMS-708163 |
Completed |
Avagacestat (BMS-708163) |
Feb. 7, 2011 |
|
| 190 |
NCT00860275 |
Drug-Drug Interaction (DDI) w/Ketoconazole or Fluconazole |
Completed |
Avagacestat (BMS-708163), Ketoconazole, Fluconazole |
Jan. 25, 2011 |
|
| 191 |
NCT01002079 |
Drug-Drug Interaction Study With Rifampin |
Completed |
Avagacestat (BMS-708163), Rifampicin |
Jan. 25, 2011 |
|
| 192 |
NCT01039194 |
Drug-Drug Interaction to Study the Effect of BMS-708163 on Pharmacokinetics (PK) of Galantamine Extended Release (ER) |
Completed |
Avagacestat (BMS-708163), Galantamine |
Jan. 25, 2011 |
|
| 193 |
NCT01042314 |
Drug-Drug Interaction Study With Aricept® (Donepezil) |
Completed |
Avagacestat (BMS-708163), Donepezil |
Jan. 25, 2011 |
|
| 194 |
NCT01057030 |
Multiple Dose Japanese Bridging Study |
Completed |
Avagacestat (BMS-708163) |
Jan. 25, 2011 |
|
| 195 |
NCT00901498 |
Relative Bioavailability Study of Four Experimental Formulations for Alzheimer's Disease |
Completed |
Avagacestat (BMS-708163) |
Jan. 7, 2011 |
|
| 196 |
NCT00979316 |
Effect on the Electrocardiographic QT Interval Corrected for Heart Rate (QTc) in Healthy Subjects |
Completed |
Avagacestat (BMS-708163), Moxifloxacin |
Jan. 7, 2011 |
|
| 197 |
NCT01253499 |
Multiple Dose Study of TRx0037 |
Completed |
TRx0037 |
Dec. 17, 2010 |
|
| 198 |
NCT00687141 |
Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD0328 in Elderly Healthy Subjects |
Completed |
AZD-0328 |
Dec. 10, 2010 |
|
| 199 |
NCT00607308 |
A Phase I, Single Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease |
Completed |
Ponezumab (PF-04360365) |
Dec. 7, 2010 |
|
| 200 |
NCT01253122 |
Comparative Bioavailability in Healthy Elderly Volunteers |
Completed |
TRx0037 |
Dec. 3, 2010 |
|
| 201 |
NCT00777361 |
Study of Uptake, Break Down and Elimination of an Investigational Drug in Healthy Volunteers |
Terminated |
AZD3480 |
Nov. 18, 2010 |
|
| 202 |
NCT00867399 |
A Safety and Tolerability Study of ABT-126 in Elderly |
Completed |
ABT-126 |
Nov. 2, 2010 |
|
| 203 |
NCT00736775 |
A Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Anti-Abeta (MABT5102A) in Patients With Alzheimer's Disease |
Completed |
Crenezumab |
Oct. 27, 2010 |
|
| 204 |
NCT00495417 |
Tolerability and Safety of Subcutaneous Administration of Affitope AD01 in Mild to Moderate Alzheimer's Disease |
Completed |
AFFITOPE AD01 |
Oct. 19, 2010 |
|
| 205 |
NCT00633841 |
Tolerability and Safety of Subcutaneous Administration of AFFITOPE AD02 in Mild to Moderate Alzheimer's Disease |
Completed |
AFFITOPE AD02 |
Oct. 19, 2010 |
|
| 206 |
NCT01093664 |
Safety/Tolerability, Immunological and Clinical Activity of a Boost Immunization With AFFITOPE AD02 |
Completed |
AFFITOPE AD02 |
Oct. 19, 2010 |
|
| 207 |
NCT00966966 |
Study Evaluating Potential Interaction Between SAM-531 And Gemfibrozil When Co-Administered |
Completed |
Cerlapirdine (SAM-531) |
Aug. 20, 2010 |
|
| 208 |
NCT00988598 |
A Brief Study To Evaluate The Safety, Tolerability, And Blood Levels Of Multiple Doses Of PF-044467943 Or Placebo In Combination With Donepezil In Subjects With Mild To Moderate Alzheimer's Disease |
Completed |
PF-04447943 |
Aug. 9, 2010 |
|
| 209 |
NCT01163825 |
Encapsulated Cell Biodelivery of Nerve Growth Factor to Alzheimer's Disease Patients |
Unknown status |
Nerve Growth Factor |
July 16, 2010 |
|
| 210 |
NCT00441987 |
Study Evaluating the Safety and Pharmacokinetics of a Single Dose of GSI-953 |
Completed |
Begacestat (GSI-953) |
June 22, 2010 |
|
| 211 |
NCT00718731 |
Study GSI-136 in Healthy Young and Healthy Elderly Subjects |
Completed |
GSI-136 |
April 2, 2010 |
|
| 212 |
NCT00745576 |
Study Evaluating The Potential Interaction Between Verapamil Immediate Release And SAM-531 When Co-Administered |
Completed |
Cerlapirdine (SAM-531) |
Feb. 8, 2010 |
|
| 213 |
NCT00990613 |
A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin |
Completed |
Latrepirdine |
Feb. 3, 2010 |
|
| 214 |
NCT00988624 |
A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine) |
Completed |
Latrepirdine |
Jan. 12, 2010 |
|
| 215 |
NCT00824590 |
A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function |
Completed |
Latrepirdine |
Dec. 30, 2009 |
|
| 216 |
NCT00017940 |
Gene Therapy for Alzheimer's Disease Clinical Trial |
Completed |
Nerve Growth Factor |
Dec. 11, 2009 |
|
| 217 |
NCT00959803 |
Study Of Single Ascending And Multiple Doses Of PF-04447943 In Japanese Subjects. |
Completed |
PF-04447943 |
Dec. 7, 2009 |
|
| 218 |
NCT00931073 |
A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers |
Completed |
Latrepirdine, Ketoconazole, Omeprazole |
Nov. 18, 2009 |
|
| 219 |
NCT00455000 |
A Phase I, Single IV Dose Of PF-04360365 In Adults With Mild To Moderate Alzheimer's Disease |
Completed |
Ponezumab (PF-04360365) |
Oct. 14, 2009 |
|
| 220 |
NCT00906191 |
Study Evaluating How Quickly And To What Extent The 14-Carbon-SAM-531 Is Absorbed/Converted/Eliminated In Male Subjects |
Completed |
Cerlapirdine (SAM-531) |
Aug. 26, 2009 |
|
| 221 |
NCT00479297 |
Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Japanese Males |
Completed |
Cerlapirdine (SAM-531) |
Aug. 7, 2009 |
|
| 222 |
NCT00739037 |
Study Evaluating PAZ-417 in Cerebrospinal Fluid in Subjects With Alzheimer's Disease |
Terminated |
Aleplasinin (PAZ-417) |
Aug. 4, 2009 |
|
| 223 |
NCT00726115 |
Study Evaluating Safety, Tolerability and Pharmacokinetics of Single and Multiple Dose of SAM-531 |
Completed |
Cerlapirdine (SAM-531) |
July 30, 2009 |
|
| 224 |
NCT00733642 |
Single Dose Escalation Study of PF-04360365 In Subjects With Mild To Moderate Alzheimer's Disease |
Completed |
Ponezumab (PF-04360365) |
July 28, 2009 |
|
| 225 |
NCT00795730 |
Multiple Dose Study Evaluating the Safety and Tolerability of NSA-789 |
Terminated |
NSA-789 |
July 21, 2009 |
|
| 226 |
NCT00838084 |
A Safety Study of LY2811376 Single Doses in Healthy Subjects |
Completed |
LY-2811376 |
July 15, 2009 |
|
| 227 |
NCT00719394 |
Study Evaluating Safety of GSI 136 in Young and Elderly Japanese Males |
Completed |
GSI-136 |
July 10, 2009 |
|
| 228 |
NCT00479349 |
Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of SAM-531 |
Completed |
Cerlapirdine (SAM-531) |
July 7, 2009 |
|
| 229 |
NCT00689559 |
Drug Interaction Study Between AZD3480 and Aripiprazole in Healthy Subjects |
Completed |
AZD3480, Aripiprazole |
July 2, 2009 |
|
| 230 |
NCT00689637 |
Drug Interaction Study Between AZD3480 and Warfarin |
Completed |
AZD3480, Warfarin |
July 2, 2009 |
|
| 231 |
NCT00831506 |
Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects |
Completed |
Latrepirdine, Digoxin |
June 12, 2009 |
|
| 232 |
NCT00239746 |
BONSAI: Biomarkers of Nonsteroidal Anti-Inflammatories |
Unknown status |
Ibuprofen |
April 29, 2009 |
|
| 233 |
NCT00117403 |
Anti-Oxidant Treatment of Alzheimer's Disease |
Completed |
Vitamin E, Ascorbic acid, Lipoic Acid, Ubidecarenone |
April 3, 2009 |
|
| 234 |
NCT00788047 |
A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of Dextromethorphan |
Completed |
Latrepirdine, Dextromethorphan |
March 9, 2009 |
|
| 235 |
NCT00684710 |
Study Evaluating the Safety, Tolerability and Activity of One Dose of PAZ-417 Given to Healthy Japanese Subjects |
Completed |
Aleplasinin (PAZ-417) |
Jan. 30, 2009 |
|
| 236 |
NCT00551772 |
A Study To Assess The Pharmacokinetics Of SB-742457 Formulated As A Capsule And A Tablet In Healthy Elderly Volunteers. |
Completed |
Intepirdine (SB-742457) |
Dec. 25, 2008 |
|
| 237 |
NCT00692510 |
Drug Interaction Study Between AZD3480 and Cytochrome P450 |
Completed |
AZD3480, Caffeine, Bupropion, Rosiglitazone, Omeprazole, Midazolam, Bilirubin |
Nov. 26, 2008 |
|
| 238 |
NCT00726726 |
Drug Interaction Study With a Potential Alzheimer's Disease Compound |
Completed |
Avagacestat (BMS-708163), Midazolam, Warfarin, Caffeine, Omeprazole, Dextromethorphan |
Nov. 5, 2008 |
|
| 239 |
NCT00765115 |
A Study of Healthy Subjects to Assess the Effect of LY450139 on Amyloid Beta Peptide Production Rate and or Dose Response. |
Completed |
Semagacestat (LY450139) |
Oct. 2, 2008 |
|
| 240 |
NCT00563732 |
Study Evaluating Potential Pharmacokinetic (PK) Interaction Between Lecozotan and Digoxin |
Completed |
Lecozotan |
Sept. 9, 2008 |
|
| 241 |
NCT00479219 |
Study Evaluating GSI-953 in Healthy Young and Alzheimer's Patients |
Completed |
Begacestat (GSI-953) |
July 10, 2008 |
|
| 242 |
NCT00499200 |
Study Evaluating Safety, Tolerability, Pharmacokinetics and 5 HT1A Receptor Occupancy |
Completed |
SRA-444 |
July 9, 2008 |
|
| 243 |
NCT00621010 |
Safety Study of CTS21166 to Treat Alzheimer Disease |
Completed |
CTS-21166 |
July 9, 2008 |
|
| 244 |
NCT00474552 |
Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-315 |
Terminated |
SAM-315 |
Feb. 18, 2008 |
|
| 245 |
NCT00499642 |
Study Evaluating the Effect of Lecozotan SR on the QTc Interval |
Completed |
Lecozotan |
Dec. 28, 2007 |
|
| 246 |
NCT00480818 |
Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Young and Elderly Subjects |
Completed |
Cerlapirdine (SAM-531) |
Dec. 11, 2007 |
|
| 247 |
NCT00479700 |
Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Subjects |
Completed |
Cerlapirdine (SAM-531) |
Dec. 10, 2007 |
|
| 248 |
NCT00452504 |
Single Ascending Dose Study of SRA-444 in Healthy Subjects |
Completed |
SRA-444 |
Dec. 5, 2007 |
|
| 249 |
NCT00479440 |
Study Evaluating the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of SAM-315 in Healthy Adults |
Completed |
SAM-315 |
Dec. 5, 2007 |
|
| 250 |
NCT00480467 |
Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-315 in Healthy Japanese Males |
Completed |
SAM-315 |
Dec. 5, 2007 |
|
| 251 |
NCT00494962 |
Study Comparing Lecozotan SR Two 5-mg Tablets Vs. Lecozotan SR One 10-mg Tablet in Healthy Subjects |
Completed |
Lecozotan |
Dec. 5, 2007 |
|
| 252 |
NCT00366483 |
Study Evaluating the Safety of Lecozotan SR in Healthy Young and Elderly Subjects |
Completed |
Lecozotan |
March 16, 2007 |
|
| 253 |
NCT00100282 |
Safety Study of PPI-1019 in Patients With Mild-Moderate Alzheimer's Disease |
Completed |
PPI-1019 |
Sept. 19, 2006 |
|
| 254 |
NCT00203320 |
TNF-Alpha Inhibition for Treatment of Alzheimer's Disease |
Completed |
Etanercept |
April 24, 2006 |
|
| 255 |
NCT00203359 |
TNF-Alpha Inhibition for Treatment of Alzheimer's Disease |
Completed |
Etanercept |
April 24, 2006 |
|